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Completed

NCT Number: NCT05156411

Strength Training With Eccentric Arm-cranking

The new training device, the eccentric arm-crank, will be examined for its training effect by this project. That the training device can be used in athletes and patients with paraplegia in the future, the so-called "testing of the applicability of this concept" will be carried out during this study. Fourteen volunteer, healthy and trained people are first tested for their upper body performance, followed by a training phase over 20 trainings and at the and the performance data is collected again. The training intensity and duration is continuously increased during the training phase.

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Key information

Conditions

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, 6207, Switzerland

About this study

At the beginning, the study design includes an familiarisation appointment with performance tests and training on the eccentric arm-crank device (KREHA). At least one week later, the first test sequence including a maximum strength test (bench press), magnetic resonance imaging (MRI) to determine the muscle cross-section area of the upper arm and a test to determine the anaerobic performance (Wingate test) is conducted. The second test sequence takes place one to three days later. This includes a handgrip strength test, an aerobic endurance test (ramp test on the arm crank ergometer with ergospirometry) and a further familiarisation training on the KREHA. The training phase starts within two weeks after the pre-tests have been completed. There are two to a maximum of three trainings per week. These take 30 to 60 minutes and take place on the KREHA device under the supervision of the study staff. The training phase lasts a maximum of twelve weeks (20 training sessions). The first test sequence is repeated five to eight days after the last workout. The second test sequence takes place at the same time interval as in the pre-tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male or female
  • age between 18 and 50 years
  • experience in strength training
  • trained (minimum two times a week)
  • healthy
  • adequately informed and confirmed per signature

Exclusion criteria

  • findings during anamnesis of study doctor
  • pregnancy

Treatment and study plan

eccentric arm-cranking training

Other

Over the twenty training sessions, able-bodied participants will exercise on the KREHA device. An arm-crank has to be decelerated, which will be rotated by a prematurely defined revolution rate and training duration. During this intervention a certain power has to be applied. During the whole time of training a continous progression in power and training duration is applied

Primary outcomes

  1. Upper body Performance

    Time frame: through study completion, an average of 20 weeks

    Peak Power - maximal reached power, generated during the 30sec Wingate arm-crank test

Secondary outcomes

  1. Endurance Oxygen consumption

    Time frame: through study completion, an average of 20 weeks

    VO2peak [ml/min/kg] - Basic Endurance test (Ergospirometry, arm-crank)

  2. Endurance Power

    Time frame: through study completion, an average of 20 weeks

    Wmax [W] - Basic Endurance test (Ergospirometry, arm-crank)

  3. Upper body Mean Power

    Time frame: through study completion, an average of 20 weeks

    Mean Power [W] - Wingate Test (arm-crank)

  4. Upper body Power - Time to Peak

    Time frame: through study completion, an average of 20 weeks

    Time to Peak [s] - Wingate Test (arm-crank)

  5. Upper body Fatigue resistance

    Time frame: through study completion, an average of 20 weeks

    Fatigue Index [%]- Wingate Test (arm-crank)

  6. Upper body Fatigue resistance

    Time frame: through study completion, an average of 20 weeks

    Fatigue Slope [W/s] - Wingate Test (arm-crank)

  7. 1RM bench press

    Time frame: through study completion, an average of 20 weeks

    One Repetition Maximum (1RM) [kg]- bench press

  8. Grip Strength

    Time frame: through study completion, an average of 20 weeks

    Maximal Force that can be generated by pressing hand towards a fist [N]

  9. Cross sectional muscle area

    Time frame: through study completion, an average of 20 weeks

    Cross sectional area of the upper arm is measured with MRI

  10. Upper Arm Circumference

    Time frame: through study completion, an average of 20 weeks

    Circumference of the upper arm is measured with measuring tape

Sponsors and collaborators

Lead sponsor

Swiss Paraplegic Research, Nottwil

Network

Registry information

Acronym: KREHA

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Dec 14, 2021
Registry last updated
Aug 24, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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