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Completed

NCT Number: NCT06675162

Effect of Muscle Strengthening Training with Pilates Reformer on Overweight/obese and Normal Body Weight Women (PRET)

This study investigates the physiological responses and the metabolic burden of a Pilates Reformer strength training session in physically inactive premenopausal women with a body mass index of 18-24.9 and 25.01-39.9. The sample included 20 women divided into two groups: 10 with normal weight (NW) and 10 with overweight/obesity (OB). In a non-randomised control design, the participants will perform a 60-minute muscle-strengthening session with Pilates Reformer equipment.

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Key information

Age range

20 year–50 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Department of Physical Education and Sport Science, Trikala, Thessaly, Greece

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About this study

Pilates Reformer (PR) is one of the most popular types of exercise worldwide and is considered a gentle and safe method for untrained and overweight people. The PR training approach has been found to contribute positively to various health conditions (vascular function, blood pressure, physical fitness, musculoskeletal problems), improving the quality of life and mental well-being of the participants. At the same time, it seems that it can have a positive effect on the lipid profile and other biochemical markers such as insulin and fasting glucose. Furthermore, muscle strengthening training with PR equipment provides better levels of mobility, increasing active range of motion, and also provides greater pelvic and trunk stability for both adult and middle-aged participants.

This study is designed to investigate the physiological and metabolic burden of a muscle-strengthening session with PR equipment in 20 pre-menopausal and physically inactive women with a body mass index (BMI) of 18-24, 99 & 25.01-39.9, as well as to determine the contribution of energy systems (mitochondrial, glycolytic) during and after the exercise. Each training session will last approximately 60 minutes, will be led by at least one trainer, and will include a warm-up of 7-10 minutes, muscle strengthening and mobility exercises of 35 minutes, and a recovery of 5 minutes. Anthropometric indicators, dietary intake, resting heart rate, blood lactate, resting metabolic rate, muscle soreness, rate of perceived exertion, blood pressure, and performance measurements will be measured at baseline. The metabolic cost during PR training session will be estimated from heart rate, blood lactate, resting oxygen uptake, exercise oxygen uptake, and excess post-exercise oxygen consumption measurements using a portable gas analyzer. After the PR training session will be measured the rate of perceived exertion, blood pressure, blood lactate, and muscle soreness levels.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be approved for participation by an orthopedist and internist
  • Have not followed any diet or nutritional supplements for weight loss in the last six months before the study
  • The group with overweight/obesity will consist of women with a body mass index of 25.01 - 39.9 kg/m2
  • Be physically Inactive in the last six months before the study.

Exclusion criteria

  • Musculoskeletal injury
  • Weight loss>10% in 6 months
  • <20 years
  • >50 years
  • Μenopause
  • Chronic diseases
  • Use of alcohol, caffeine and any type of ergogenic supplements or medication during the study
  • Physically active.

Treatment and study plan

Pilates Reformer Training

Other

Participants will perform a 60-minute Pilates Reformer muscle-strengthening session. The training will include a 7-10 minute warm-up, 35 minutes of muscle strengthening and mobility exercises and a 5-minute recovery. During the training, the physiological responses and the energy expenditure of the participants will be recorded.

Primary outcomes

  1. Change in exercise-induced energy expenditure

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Exercise energy expenditure (kcal) will be measured using a portable indirect calorimetry system

  2. Change in excess post-exercise oxygen consumption (EPOC)

    Time frame: At 30 minutes after the exercise session (single bout lasting 60 minutes)

    EPOC (kcal) will be measured using a portable indirect calorimetry system

  3. Change in blood lactate concentration (BLa)

    Time frame: At pre- and post-exercise session (single bout) at 4 minutes post-exercise

    BLa (mmol/L) concentration will be measured in a microphotometer with commercially available kits

  4. Change in heart rate

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Heart rate (bpm) will be measured with a wearable heart rate monitor

  5. Change in perceived exertion

    Time frame: At pre- and post-exercise session (single bout) at 4 minutes post-exercise.

    Rating of perceived exertion (RPE) will be measured with the Borg scale (0-10)

  6. Respiratory Exchange Ratio (RER)

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Respiratory Exchange Ratio (RER) will be measured using a portable indirect calorimetry system

  7. Breath Frequency (BF)

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Breath Frequency (BF) will be measured using a portable indirect calorimetry system

  8. Change in oxygen consumption

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Oxygen consumption will be measured using a portable indirect calorimetry system

Secondary outcomes

  1. Body weight

    Time frame: At baseline and at 40 minutes after the exercise session.

    Body weight will be measured on a beam balance with a stadiometer

  2. Body height

    Time frame: At baseline

    Body height will be measured on a beam balance with a stadiometer

  3. Body mass index (BMI)

    Time frame: At baseline

    BMI will be calculated using the Quetelet's equation

  4. Waist circumference (WC)

    Time frame: At baseline

    WC (cm) will be measured using a Gullick II tape

  5. Hip circumference (HC)

    Time frame: At baseline

    HC (cm) will be measured using a Gullick II tape

  6. Waist-to-hip ratio (WHR)

    Time frame: At baseline

    WHR will be calculated by dividing the waist by the hip measurement

  7. Resting metabolic rate (RMR)

    Time frame: At baseline

    RMR (kcal) will be measured using a portable open-circuit indirect calorimeter with a ventilated hood system

  8. Body fat (BF)

    Time frame: At baseline

    Body fat (%) will be assessed by whole-body dual-energy X-ray absorptiometry (DXA)

  9. Fat mass (FM)

    Time frame: At baseline

    FM (kg) will be assessed by whole-body dual-energy X-ray absorptiometry (DXA)

  10. Fat-free mass (FFM)

    Time frame: At baseline

    FFM (kg) will be assessed by whole-body dual-energy X-ray absorptiometry (DXA)

  11. Bone mass density

    Time frame: At baseline

    Bone mass density will be measured by using Dual-emission X-ray absorptiometry

  12. Bone mass content

    Time frame: At baseline

    Bone mass content will be measured by using Dual-emission X-ray absorptiometry

  13. Peak Maximal oxygen consumption (Peak VO2)

    Time frame: At baseline

    Peak VO2 will be estimated by open circuit spirometry via breath by breath method

  14. Dietary intake

    Time frame: At baseline

    Dietary intake will be assesed over a 7-day period using diet recalls

  15. Systolic Blood Pressure

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Systolic Blood Pressure will be examined using a sphygmomanometer

  16. Diastolic Blood Pressure

    Time frame: At pre-exercise, 60 minutes during PR training, and 30 minutes after the exercise session (single bout lasting 60 minutes)

    Diastolic Blood Pressure will be examined using a sphygmomanometer

  17. Rest Heart Rate

    Time frame: At baseline

    The rest heart rate will be estimated using a heart rate monitor

  18. Evaluation of physical activity (PA)

    Time frame: At baseline

    The PA will be evaluated for seven days before the intervention via accelerometry

Sponsors and collaborators

Lead sponsor

University of Thessaly

Other

Registry information

Official study title

The Physiological Responses of Muscle Strengthening Training with Pilates Reformer in Overweight-obese Women and Women with Normal Body Weight

Acronym: PRET

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Nov 5, 2024
Registry last updated
Jan 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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