Stored RBC Transfusion and Immonomodulation

Transfusion of RBC is associated with post operative infections. Our hypothesis is that stored blood could be related with increased post operative infection risk. Surgical patients transfused during the operation or immediately after will be included in our study. Patients will receive fresh or old blood during the whole recovery.

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Key information

Conditions

Infections

Age range

18 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sant'Anna Hospital

Ferrara, 44121, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients transfused during or in 24h after surgical operation

Exclusion criteria

Patients transfused during the 30 days before the operation
Immunodepressed patients
Infections during the 30 days before operations
Emergency surgery

Treatment and study plan

Fresh RBC

Other

Patients will receive fresh blood only

Old RBC

Other

Other names: Patients will receive blood stored for 14 days or more

Primary outcomes

Incidence of infections

Time frame: 28 days

Sponsors and collaborators

Lead sponsor

Università degli Studi di Ferrara

Other

Registry information

Official study title

Infective Complication After Surgery and Transfusion of Allogenic RBC Fresh or Stored

Important dates

Study start: 2013
Primary completion: 2015
Study completion: 2015
First posted: Nov 5, 2013
Registry last updated: Feb 3, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed