Metastasis-directed Therapy for Oligometastases of Breast Cancer
NCT06135714
Breast Cancer, Breast Diseases
Tokyo, Japan
View Trial DetailsNCT Number: NCT07397585
Oligometastatic breast cancer is a condition in which breast cancer has spread to a small number of other parts of the body. Patients with this type of disease may live longer than those with more widespread metastases. In addition to standard treatments that act on the whole body, such as chemotherapy or hormonal therapy, these patients might also benefit from local treatments that directly target the cancer spots. One of these local treatments is stereotactic body radiotherapy (SBRT), a non-invasive radiation treatment that delivers high doses of radiation in a few sessions. In the past, most of the evidence about the benefit of local treatments came from surgery. More recently, there has been growing interest in SBRT because it does not require surgery. However, the results of studies so far have not been consistent.The goal of this multicenter retrospective study is to better understand whether SBRT can improve disease control and survival in patients with breast cancer that has spread to a limited number of sites outside the brain.
Interested in participating?
Request Info18 year and older
All sexes
Observational
Ospedale Perrino, Brindisi, BR, Italy
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Time frame: from January 2010 to December 2023
years of survival without disease progression assessed by imaging
Time frame: from January 2010 to December 2023
time between treatment and disease recurrence assessed by imaging
Time frame: From January 2010 to December 2023
the time from diagnosis or initiation of treatment until death from any cause
Time frame: from January 2010 to December 2023
Evaluation of toxicities related to radiotherapy treatment using the scale CTCAE (Grade 1: Mild, Grade 2: Moderate, Grade 3: Severe, Grade 4: Life-threatening, Grade 5: Death)
Contact information is provided by the study sponsor or research team.
Laura Bonavita, Master Degree
CONTACT
Ruggero Spoto, MD, Radiation oncologist
CONTACT
Istituto Clinico Humanitas
Other
Acronym: ORIETTA
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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