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Completed

NCT Number: NCT00186225

Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors

To evaluate the use of unrelated donors for hematopoietic cell transplantation in the treatment of hematologic and lymphoid malignancies.

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Key information

Conditions

Blood Cancer Blood and Marrow Transplant (BMT) Hematologic Diseases Hematologic Neoplasms Hemic and Lymphatic Diseases Neoplasms Neoplasms by Site

Age range

4 week–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Stanford University School of Medicine

Stanford, California, 94305, United States

About this study

Stem Cell Transplantation from Matched Unrelated or Partially Matched Related Donors Using a Preparatory Regimen Consisting of Fractionated Total Body Irradiation (FTBI) and Cyclophosphamide (CY). To administer high dose radio-chemotherapy followed by stem cell transplantation from a matched unrelated donor or a partially matched related donor.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

- acute leukemia

  • chronic leukemia
  • lymphoblastic lymphoma
  • MDS
  • MPS Exclusion Criteria:- organ dysfunction
  • HIV positive

Treatment and study plan

ablative allogeneic hematopoietic cell transplantation

Procedure

Primary outcomes

  1. oxicity and efficacy of TBI and cyclophosphamide as preparation for hematopoietic cell transplantation from partially matched and unrelated donors.

Secondary outcomes

  1. Overall Survival

  2. Event Free Survival

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Official study title

Stem Cell Transplantation From Matched Unrelated or Partially Matched Related Donors Using a Preparatory Regimen Consisting of Fractionated Total Body Irradiation (FTBI) and Cyclophosphamide (CY)

Important dates

Study start
1989
Primary completion
2007
Study completion
2010
First posted
Sep 16, 2005
Registry last updated
Apr 9, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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