Splenic Surgery for Hydatid Spleen in S… | Clinical Trial

Key information

Conditions

Spleen; Cyst, Hydatid (Manifestation) Cestode Infections Cysts Echinococcosis Helminthiasis Infections Neoplasms Parasitic Diseases Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

16 year–65 year

Sex eligibility

All sexes

Study type

Observational

About this study

Background:

Although hydatid disease affects many organs in the human body, splenic hydatid represents about 0.8-4% of all human echinococcosis cases. Until recently, splenectomy was the recommended surgical procedure for splenic hydatid. Since 1980 there has been an increasing tendency to use conservative option to deal with such pathology.

Aim of the study:

To evaluate our experience in open splenic-preserving surgery for splenic hydatid in a single institutional study.

Patient and methods:

A retrospective study. Ten patients with splenic hydatid were operated upon from August 2013 to January 2018 in our medical centre. Spleen has affected alone in 7 cases, liver and spleen were affected in 3 cases, and one of them had intraperitoneal cyst affection in addition. The diagnosis confirmed mainly by ultrasonography. In some cases, it computed tomography CT scan, and magnetic resonance imaging MRI were needed. Chest X-ray had taken for all patients to exclude pulmonary hydatid. The open surgical procedure used. Isolation of the field, aspiration of cystic fluid and injection of 1% cetrimide solution, re-aspiration, endocystectomy, suturing of cystic edges over intracystic tube drain. All surgery did under cover of albendazole pre and postoperative 15mg/kg/day.

Results:

No significant intraoperative and postoperative complications. No reoperation was needed. Hospital stays 3-5 days. No recurrence after (1-3) year follow-up. However, three patients missed follow-up after two years.

Conclusion:

Our experience in splenic hydatid encourages us to use splenic-preserving surgery whenever possible instead of splenectomy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Single hydatid spleen Primary spleen hydatid

-

Exclusion criteria

Multiple splenic hydatid Rupture hydatid spleen

Treatment and study plan

Cystic enculation of spleen hydatid

Procedure

Preoperative preparation did according to the general condition of the patient and fitness for anaesthesia. Laparotomy did under general anaesthesia, supine position, the abdomen opened either by midline or left subcostal incision. Identification of splenic hydatid cyst. Exploration of the peritoneal cavity for undetected hepatic or peritoneal hydatid preoperatively. Isolation of operative field by packs socked with hypertonic solution (20 -30 % hypertonic saline). Aspiration of the cyst fluid. Injection of suitable amount about 5 ml of (1 % of cetramid) solution and waiting for at least 5 minutes and then re-aspiration. The spleen is not needed to mobilize. Extraction of the endocyst and washing of the cavity with normal saline. Occupying the cystic cavity intracystic drain. Perioperative and postoperative close observation of the patient for an anaphylactic reaction or any other complication. Follow-up of the patient until discharge from hospital on (3th - 5th) days.

Primary outcomes

splenic sparing surgery for hydatid spleen

Time frame: 3 year

Six of them males and four females, their age range from 5- 40 years (mean 23.6 years). Hydatid spleen alone was found in seven cases while splenic and liver hydatid was found in three cases one of them had peritoneal hydatid affection in addition. Hospital stay was ranged from 3-5 days.

Sponsors and collaborators

Lead sponsor

Jabir Ibn Hayyan Medical University

Other

Registry information

Official study title

Splenic Preserving Surgery in Hydatid Spleen

Important dates

Study start: 2013
Primary completion: 2018
Study completion: 2020
First posted: May 18, 2021
Registry last updated: May 18, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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