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NCT Number: NCT06433817

Spectral CT in Radiotherapy for Cervical Cancer

The purpose of this study was to explore the potential application of spectral CT for radiotherapy in cervical cancer.

Recruiting

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Key information

Conditions

Cervical Cancer Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Genital Neoplasms, Female Neoplasms Neoplasms by Site Radiotherapy Urogenital Diseases Urogenital Neoplasms Uterine Cervical Diseases Uterine Cervical Neoplasms Uterine Diseases Uterine Neoplasms

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Peking Union Medical College Hospital

Beijing, Beijing Municipality, 100010, China

Location status: Recruiting

Location contact

Zheng Zeng, MD.

CONTACT

[email protected]

86 01069154073

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients were confirmed cervical cancer by pathology
  • patients were treated with concurrent chemoradiotherapy
  • Spectral CT scans acquisition performed during the arterial phase and venous phase
  • All the patients underwent a 18F-FDG PET/CT before treatment

Exclusion criteria

  • CT without spectral scans
  • History of allergy to intravenous contrast
  • Pregnant or potentially pregnant female subjects

Treatment and study plan

Spectral computed tomography scan

Radiation

Spectral CT scans acquisition performed during the arterial phase and venous phase for cervical cancer

Primary outcomes

  1. Comparison of spectral CT derived data with response evaluation in cervical cancer

    Time frame: through study completion, an average of 2 year

    To evaluate the tumor response of using quantitative parameters in spectral CT for cervical cancer patients according to RECIST 1.1

Secondary outcomes

  1. Identifying metastatic lymph nodes in cervical cancer with spectral CT

    Time frame: through study completion, an average of 2 year

    To evaluate the diagnostic performances of using spectral CT for identifying metastatic lymph nodes in patients with cervical cancer

  2. Application of energy spectrum CT in brachytherapy of cervical cancer

    Time frame: through study completion, an average of 2 year

    The ability to reduce metal artifact and assist in target delineation

Study contacts

Contact information is provided by the study sponsor or research team.

Fuquan Zhang, Porf

CONTACT

[email protected]

86 01069154072

Sponsors and collaborators

Lead sponsor

Peking Union Medical College Hospital

Other

Registry information

Official study title

The Clinical Research of Spectral CT in Radiotherapy for Cervical Cancer

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
May 30, 2024
Registry last updated
May 30, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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