Skip to main content
OpenTrials
Completed

NCT Number: NCT03165357

Sodium Bicarbonate Supplementation in Athletes

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Supplementation Sport

Age range

20 year–43 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Poznan University of Life Sciences, ul.Wojska Polskiego 31

Poznan, Wielkopolska, 60-624, Poland

About this study

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • written consent to participate,
  • a current medical clearance to practice sports,
  • training experience: at least 2 years (of CrossFit training),
  • minimum of 3 workout sessions (CrossFit) a week,
  • 20-43 years.

Exclusion criteria

  • current injury,
  • any health-related contraindication,
  • declared general feeling of being unwell,
  • unwilling to follow the study protocol.

Treatment and study plan

Sodium bicarbonate supplementation

Dietary Supplement

Placebo treatment

Dietary Supplement

Primary outcomes

  1. Changes in aerobic capacity after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    The incremental cycling test (ICT)

  2. Changes in specific performance capacity after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    The CrossFit-specific physical fitness test: Fight Gone Bad (FGB)

Secondary outcomes

  1. Changes in fat mass and fat free mass after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Fat mass (kg) and fat free mass (kg) analysis

  2. Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Red blood cells (RBC) [mln/mm³] and white blood cells (WBC) [mln/mm³] concentration analysis

  3. Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Hemoglobin (Hb) [g/dl] and glucose [g/dl] concentration analysis

  4. Changes in blood hematocrit levels after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Hematocrit (HCT) [%] level analysis

  5. Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Lactate [mmol/L] and pyruvate [mmol/L] concentration analysis

  6. Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation

    Time frame: Baseline and after 10 days

    Creatine kinase [U/L] and lactate dehydrogenase [U/L] activity analysis

Sponsors and collaborators

Lead sponsor

Poznan University of Life Sciences

Other

Collaborators

  • Poznan University of PhysED

Registry information

Official study title

The Effect of Sodium Bicarbonate Supplementation on Physical Capacity and Body Composition in Trained Athletes

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
May 24, 2017
Registry last updated
May 24, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.