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Completed

NCT Number: NCT06716736

Socket Preservation After Surgical Extraction of Impacted Lower Third Molar

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

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Key information

Conditions

Socket Preservation

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mansoura University

Al Mansurah, Eldakahlia, 35511, Egypt

About this study

The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin (sticky tooth) versus bone allografts and collagen cone after surgical extraction of the horizontally impacted lower third molar

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fresh extracted socket of horizontally impacted mandibular third molar
  • Co-operative patients willing to complete the follow-up periods.
  • Patients age from 18-35 years.
  • Good oral hygiene.

Exclusion criteria

  • Any pathological condition at the site of surgery.
  • Patients with systemic diseases that contra-indicate the surgical procedure such as uncontrolled diabetes mellitus, bleeding disorders, serious osseous disorders and mental disorders.
  • Smokers .
  • Pregnancy.

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Treatment and study plan

socket preservation using dentine graft mixed with i-PRF

Biological

surgical extraction of horizontally impacted third molar , placement of dentin graft mixed with i-PRF inside the socket , suturing

socket preservation using bone allograft

Biological

surgical extraction of horizontally impacted third molar , placement of bone allograft inside the socket , suturing

socket preservation using collagen cone

Biological

surgical extraction of horizontally impacted third molar , placement of collagen cone inside the socket , suturing

Primary outcomes

  1. bone resorption distal to second molar

    Time frame: 3 months after extraction

    by measuring bone level immediate and 3 months after extraction on CBCT

Secondary outcomes

  1. bone density

    Time frame: 3 months after extraction

    using CBCT 3 month after extraction

  2. edema

    Time frame: 4 days after extraction

    by measuring distance between predetermined anatomical landmarks:

    • Mandibular angle and canthus of the eye.
    • Mandibular angle and corner of the mouth.
    • Mandibular angle and tragus.
    • Mandibular angle and pogonion.

  3. pain after surgical extraction

    Time frame: 4 days after extraction

    using numerical rating scale

Sponsors and collaborators

Lead sponsor

Wael Mohamed

Other

Registry information

Official study title

Socket Preservation Using Autogenous Particulate Dentin in Combination With Liquid Platelet-rich Fibrin Versus Bone Allografts and Collagen Cones After Surgical Extraction of Impacted Lower Third Molar

Important dates

Study start
2022
Primary completion
2023
Study completion
2024
First posted
Dec 4, 2024
Registry last updated
Dec 4, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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