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Completed

NCT Number: NCT07665918

Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone

To evaluate the effect of Omega-3 in preserving bone after extraction

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Key information

Conditions

Omega-3 Fatty Acids Esthetic Zone Socket Preservation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Dentistry

Cairo, Egypt

About this study

The evaluation of the effect of omega-3 on the bone of the socket with changes in the dimensions like vertical and horizontal bone changes 3months after extraction .

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with non-restorable remaining roots.
  • Patients free of systemic conditions that might affect the surgical procedure or the quantity or quality of bone (uncontrolled hypertension, uncontrolled diabetes).

Exclusion criteria

  • Patients below 18 years old
  • Patients with hypersensitivity to omega-3, drug formulations or allergic to seafood.
  • Pregnant or lactating females
  • Patients undergoing chemotherapy or radiotherapy
  • Smokers

Treatment and study plan

Omega 3 Fish Oil supplements

Dietary Supplement

omega-3 fatty acid supplement

Other names: Omega-3

Primary outcomes

  1. Post-operative pain

    Time frame: immediately after extraction and the second day after extraction

    Visual Analogue Scale score "VAS score" From 0-10 scores score 0 is no pain which is the best 1-4 is mild pain 5 is moderate pain from 5 -10 pain is getting worse and 10 is the worst

Secondary outcomes

  1. Radiographic bone changes "horizontal bone changes " using Cone beam CBCT

    Time frame: before extraction and 3months after omega 3 placement

    Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter

  2. Radiographic bone changes " Vertical bone fill" using CBCT

    Time frame: before and after 3 months of extraction and omega-3 placement

    Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the difference in vertical bone measurements in millimeter

  3. Radiographic bone changes "Bone density" using CBCT

    Time frame: 3 months after extraction and placement of omega-3

    Performing one CBCT before extraction and one new CBCT after 3 months of extraction and omega-3 placement then comparing both CBCTs by J image computer program to get the radiographic bone changes in millimeter and Hounsfield units

  4. Histological examination

    Time frame: after 3months of extraction during implant placement bone is taken using trephine bur

    using Hematoxylin and Eosin staining to measure the area of newly formed bone "Percentage"

  5. Healing Index "HI" by Landry et al using scores

    Time frame: after 3months of omega 3 placement

    Using Landry et al wound healing index to measure soft tissue reaction changes. Each category is scored from 1 to 5, with 1 indicating very poor healing and 5 indicating excellent healing. The HI is a useful tool for assessing the quality of wound healing and guiding postoperative interventions.

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Evaluation of OMEGA-3 Effect in Alveolar Socket Preservation in Aesthetic Zone: A Case Series

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 24, 2026
Registry last updated
Jun 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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