Department for Health, University of Bath
Bath, BA2 7AY, United Kingdom
NCT Number: NCT06333184
Glycaemic responses to fruit smoothies may depend on the food matrix (e.g., degree of processing and physical structure), ingestion rate, dose ingested and fibre content. Furthermore, the method of sampling could alter inferences. The aim of this project is to characterise how these factors affect the glycaemic response to a commercially available fruit smoothie. Participants will ingest 7 different test drinks in a randomised, crossover design with fingerstick capillary blood sampling alongside continuous glucose monitors. Test drinks will include a glucose reference (CONTROL), the commercial product matched for carbohydrate to CONTROL (PRODUCT), equivalent carbohydrate ingested as whole fruits (WHOLE), equivalent carbohydrate ingested as blended fruits (WHOLE), equivalent carbohydrate as the commercial product ingested slowly (SLOW), equivalent carbohydrate as the commercial product ingested with additional fibre (FIBRE), and the commercial product ingested in a dose typically bought (DOSE). These data will provide insight into how the food matrix and different patterns of ingestion can alter the glycaemic response to a fruit smoothie, and how the measurement method may alter interpretations.
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Notify Me18 year–65 year
All sexes
Interventional
Not applicable
Bath, BA2 7AY, United Kingdom
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Fruit ingested in whole form or as either commercially available, or home-made smoothies
Time frame: 120 min
The difference in glycaemic index [2-hour incremental area under the curve (mmol/L-1x120 min) for PRODUCT relative to CONTROL expressed as a percentage] in capillary blood samples versus continuous glucose monitors.
Time frame: 120 min
The difference in glycaemic index [2-hour incremental area under the curve (mmol/L-1x120 min) for all other conditions (WHOLE, BLEND, SLOW, FIBRE, DOSE) relative to CONTROL expressed as a percentage] in capillary blood samples versus continuous glucose monitors.
Time frame: 120 min
The effect of condition-by-blood sampling (capillary vs continuous glucose monitor) interaction for the 2-hour incremental area under the curve for all conditions.
Time frame: 120 min
Comparisons between conditions for the 2-hour incremental area under the curve relative to CONTROL using capillary blood glucose.
Time frame: 120 min
Comparisons between conditions for the 2-hour incremental area under the curve relative to CONTROL using continuous glucose monitors.
Time frame: 120 min
The condition-by-blood sampling interaction for the postprandial peak glucose concentrations (mmol/L)
Time frame: 120 min
The condition-by-blood sampling interaction for the time to peak glucose concentrations (min)
University of Bath
Other
Examining the Blood Sugar Response to Fruit Smoothie Consumption
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