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NCT Number: NCT06917222

Slide Tracheoplasty Versus Tracheal Resection Anastomosis in Acquired Tracheal Stenosis

Aim of the Work To compare the clinical outcomes between patients will undergo slide tracheoplasty and those will undergo tracheal resection anastomosis for acquired tracheal stenosis.

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Key information

Conditions

Tracheal Stenosis Respiratory Tract Diseases Subglottic Stenosis Tracheal Diseases

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients with grade III, IV acquired tracheal stenosis (e.g., due to trauma, prolonged intubation) regardless their age or sex.
  • Patient with symptomatic high grade II acquired laryngotracheal stenosis after failure of endoscopic interventions.
  • Clinical indications for surgical intervention (Symptoms of airway obstruction).
  • Feasible for surgical intervention.

Exclusion criteria

  • congenital tracheal stenosis
  • Malignant stenosis.
  • Severe comorbidities that contraindicate the surgery.
  • Patients refusing to sign the consent.

Treatment and study plan

Slide tracheoplasty

Procedure

Management of tracheal stenosis by slide tracheoplasty

Tracheal resection anastomosis

Procedure

Management of tracheal stenosis by tracheal resection anastomosis

Primary outcomes

  1. Success Rate of Procedure

    Time frame: 3-6 months

    Defined as the absence of stridor or the need for re-intervention within a defined follow-up period (3 months

Secondary outcomes

  1. Complication Rates

    Time frame: 3 months

    Evaluation of perioperative complications:

    • Immediate Complications: Airway obstruction, pneumothorax, anastomotic leak, or accidental injury to surrounding structures (e.g., RLN).
    • Delayed Complications: Stenosis, granulation tissue formation, tracheomalacia, or infection (e.g., mediastinitis).
    • Mortality Rate: Intraoperative and 30-day mortality rates

  2. Duration of Hospital Stay

    Time frame: 3 months

    Measured from the day of surgery to discharge

  3. Time to Decannulation

    Time frame: 3 months

    Time taken for patients to be successfully decannulated, which can be indicative of recovery and airway stability.

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed Elsobki, Associated professor

CONTACT

[email protected]

+20 122 7505929

Eslam Hamed Abdou, Assistant lecturer

CONTACT

[email protected]

+201015566532

Sponsors and collaborators

Lead sponsor

Mansoura University Hospital

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Apr 8, 2025
Registry last updated
Sep 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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