SleeperOne® 5 Intraosseous Anesthesia in MIH

Molar-incisor hypomineralization (MIH) is a developmental enamel defect that frequently presents with hypersensitivity, post-eruptive enamel breakdown, and an increased risk of restorative treatment failure. Achieving effective local anesthesia in children with MIH can be challenging because hypersensitive teeth often exhibit increased pain during anesthetic administration and restorative procedures. These factors may compromise patient cooperation and the quality of dental treatment.

Computer-controlled local anesthetic delivery systems have been developed to improve injection comfort by controlling the rate and pressure of anesthetic administration. The SleeperOne® 5 system allows computer-controlled intraosseous anesthesia and may provide more effective pain control than conventional local anesthesia during restorative treatment of MIH-affected teeth.

The purpose of this study was to compare SleeperOne® 5-assisted intraosseous anesthesia with conventional local anesthesia in children undergoing restorative treatment of permanent first molars affected by MIH.

The study was conducted as a randomized split-mouth clinical trial in which each participant received both anesthetic techniques during separate treatment sessions. The order of the interventions was determined using computer-generated randomization, allowing each participant to serve as his or her own control. All clinical procedures were performed under standardized conditions by the same operator.

The study was designed to evaluate whether computer-controlled intraosseous anesthesia could improve pain control and patient comfort during restorative treatment of children with MIH compared with conventional local anesthesia.

Inclusion criteria

Children aged 8 to 14 years. Bilateral symmetrical MIH-affected permanent first molars requiring restorative treatment.

MIH diagnosed according to EAPD criteria. Positive or definitely positive Frankl Behavior Rating Scale. Parent or guardian provided written informed consent.

Exclusion criteria

Acute pulpal or periapical pathology. Developmental dental anomalies other than MIH. Allergy to local anesthetic agents. Medical contraindication to local anesthesia. Analgesic or anti-inflammatory drug use within 24 hours before treatment. Cognitive or communication disorders affecting study assessments. Uncooperative behavior.