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Completed

NCT Number: NCT03220594

Serum AMH Levels in Patients Who Underwent Hypogastric Artery Ligation

To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.

Completed

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Key information

Conditions

AMH

Age range

18 year–40 year

Sex eligibility

Female

Study type

Observational

Primary location

Kanuni SSTRH

Istanbul, 34303, Turkey (Türkiye)

About this study

To measure and compare serum antimullerian hormone levels in patients who underwent hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy and postpartum control. The procedures performed as an emergency life saving method during delivery. The reasons for hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy were obstetric hemorrhage mainly uterine atony.

The serum levels of antimullerian hormone were measured 6 months after the operations and compared with matching postpartum controls. Serum levels of FSH, LH, PRL and TSH were also measured 6 months after the operation. Further, antral follicle count measured along with the aforementioned blood tests.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 18- 40 years
  • no systemic or endocrine diseases
  • patients who had hypogastric artery ligation and/or hysterectomy
  • healthy postpartum patients as controls

Exclusion criteria

  • history of chemotherapy and/or radiotherapy
  • Obese patients
  • patients with previous/present endometriosis
  • patients with PCOS

Treatment and study plan

hypogastric artery ligation

Procedure

hypogastric artery ligation is the ligation of the internal iliac artery to stop bleeding related to obstetrics obstetric hemorrhage Hysterectomy is the removal of the uterus if bleeding can't stop by hypogastric artery ligation

Other names: hysterectomy

Primary outcomes

  1. Ovarian reserve

    Time frame: 6 months

    To evaluate postoperative ovarian reserve using anti-mullerian hormones and other ovary related hormones including FSH,LH

Sponsors and collaborators

Lead sponsor

Kanuni Sultan Suleyman Training and Research Hospital

Other

Registry information

Official study title

Serum Antimullerian Hormone Levels in Patients Who Underwent Hypogastric Artery Ligation

Important dates

Study start
2017
Primary completion
2017
Study completion
2017
First posted
Jul 18, 2017
Registry last updated
Oct 2, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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