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OpenTrials
Completed

NCT Number: NCT04311827

Serratus Anterior Plane Block for Improving Pain and Respiratory Function in Patients With Multiple Rib Fractures

This is an observational study which will evaluate the efficacy of the serratus anterior plane block for treating pain and respiratory capacity in patients with multiple rib fractures. When resources are available for a SAPB to be performed, patients will receive this block in addition to traditional pain medications, while at other times, patients will receive traditional pain medications only.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Stanford University Hospital

Palo Alto, California, 94305, United States

About this study

Pain management by systemic analgesics and by nerve blocks are both standard of care and used in Emergency Department (ED) depending on the resources available. Not all ED physicians are trained or comfortable with the serratus anterior nerve block and thus it is not always available to patients and is provider dependent.

This is an observational study where patients with multiple rib fractures will receive either a serratus anterior plane block (SAPB) in addition to traditional forms of pain control when providers trained to perform the block are available, or will receive traditional forms pain control if trained personnel are not available. In addition to the serratus anterior plane block, standard forms of pain control in the Stanford Emergency Department include: oral or parenteral acetaminophen, oral or parenteral NSAIDs, oral or parenteral opiates, parenteral lidocaine, and parenteral ketamine.

Retrospective evaluation of the allocation of patients to either nerve block or no nerve block will be dictated by physician ability, time and resources to do the block. The efficacy of the block will be evaluated by serial measurements of pain score and respiratory capacity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age greater or equal to 18 years of age
  • Presentation to Stanford University Hospital Emergency Department within 12 hours of a traumatic incident
  • Three or more anterior and/or lateral unilateral rib fractures diagnosed by CT
  • GCS 15, with the ability to discern and describe pain from rib fractures and give consent
  • Presentation to the Emergency Department between 7am and 11pm (for identification by research assistants)

Exclusion criteria

  • Posterior rib fractures
  • Bilateral rib fractures
  • Sternal fracture
  • Known allergy to local anesthetics
  • Pregnancy
  • Significant coagulopathy
  • Hemodynamic instability

Treatment and study plan

Serratus anterior plane block

Other

Injection of bupivacaine 75mg above the serratus anterior facial plane in the anterior axillary line

Primary outcomes

  1. Change in pain score

    Time frame: Before and 3 hours after analgesia administration

    Patient reported pain score from 0-10 (0 - no pain, 10 = worst pain imaginable).

  2. Change in incentive spirometry volume

    Time frame: Before and 3 hours after analgesia administration

    Maximum inspiratory respiratory volume (measured in ml) recorded on single use of incentive spirometer device

Secondary outcomes

  1. Analgesia administration

    Time frame: Up to 3 days

    Dosage of analgesic medications administered for pain during ED visit and hospital stay

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Collaborators

  • Society for Academic Emergency Medicine

Registry information

Official study title

The Effect of the Serratus Anterior Plane Block in Improving Pain and Respiratory Function in Trauma Patients Presenting to the Emergency Department With Multiple Rib Fractures.

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Mar 17, 2020
Registry last updated
Aug 25, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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