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Active, Not Recruiting

NCT Number: NCT02431871

Sequelae of Developmental Dysplasia of the Hip

The aim of this study is to assess long term effects of developmental dysplasia of the hip (DDH) to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their childhood with age and sex matched controls.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Age range

10 year–30 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Oulu; Oulu University Hospital

Oulu, 90100, Finland

About this study

Developmental dysplasia of the hip (DDH) is the most common musculoskeletal disorder in infancy. However there are few reports of long term effects of successfully treated DDH. Incidence of DDH in neonatal period is approximately 1-10/1000 depending on screening protocols used, the age of the infant during screening and which ultrasonographic findings are considered normal and which DDH. The prevalence of hip dysplasia in adult population is grossly 4 % when using Wibergs Centre-Edge (CE) ≤ 20° as definition of dysplasia. It is still unclear, what is the relation between adult acetabular dysplasia and developmental dysplasia in children. Hip dysplasia overall is a major contributing factor in hip osteoarthrosis and total hip replacement in young adults.

The aim of this study is to assess long term effects of developmental dysplasia of the hip to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their early childhood with age and sex matched controls.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for person treated for DDH:

  • DDH has been diagnosed by clinical examination, ultrasound examination or by radiological examination and treatment begun before age of 1,5 years.
  • Treated in Oulu University Hospital

Exclusion criteria

  • neurological or developmental condition which can influence hip development such as cerebral palsy or spina bifida
  • other significant congenital anomalies of musculoskeletal system such as club feet

Treatment and study plan

Primary outcomes

  1. Wibergs Centre-Edge Angle

    Time frame: 10 - 30 years after DDH has been treated

    angle degree

Secondary outcomes

  1. The Copenhagen Hip and Groin Outcome Score (HAGOS)

    Time frame: 10 - 30 years after DDH has been treated

    score in numbers

  2. Oral Heath Impact Profile

    Time frame: 10 - 30 years after DDH has been treated

    Oral Heath Impact Profile (OHIP-14) -questionaire to assess Oral Health-related Quality of Life

  3. Occlusal asymmetries

    Time frame: 10 - 30 years after DDH has been treated

    Determined by dental examination and intraoral scan

  4. Presence of facial asymmetry

    Time frame: 10 - 30 years after DDH has been treated

    Determined by 3D -photogrammetric images

Other outcomes

  1. Hip deformity

    Time frame: 10 - 30 years after DDH has been treated

    Determined by hip radiograph

  2. Asymmetry in clinical hip examination

    Time frame: 10 - 30 years after DDH has been treated

    Determined by clinical hip examination

Sponsors and collaborators

Lead sponsor

University of Oulu

Other

Registry information

Official study title

Structural and Functional Sequelae of Developmental Dysplasia of the Hip

Important dates

Study start
2016
Primary completion
2022
Study completion
2026
First posted
May 1, 2015
Registry last updated
Nov 29, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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