Safety and Tolerability of EO2002

Key Inclusion Criteria:

• Age ≥ 18 years.
• Subject has uncomplicated history of cataract that has progressed to a level requiring standard cataract extraction with intraocular lens implant surgery.
• Decreased endothelial cell count

Exclusion criteria

All ocular criteria apply to study eye unless otherwise noted.

• Other corneal disease
• Macular disease that in the investigator and/or sponsor's opinion would limit the ability of the subject to demonstrate improvement in BCVA.
• Descemet membrane detachment.
• History of uveitis or other ocular inflammatory disease.
• History of incisional glaucoma surgery
• Prior incisional eye surgery within 3 months prior to study treatment or penetrating or endothelial keratoplasty.
• History of ocular neoplasm.
• ETDRS BCVA in the fellow eye is worse than 35 letters (Snellen equivalent of 20/200).
• Female who is pregnant, nursing, or planning to become pregnant, or who is of childbearing potential and not using a reliable means of contraception during the study.
• Subject is currently participating in or has participated within the last 3 months in any other clinical trial of an investigational drug by ocular or systemic administration.
• Any concomitant medical or psychological condition that could interfere with study participation or is otherwise not suitable for entry into the study in the opinion of the investigator.