Role of Psychiatric Profile in Prehabituated Patients After Vestibular Schwannoma Surgery

The aim of this study is to assess effect of psychiatric profile on visual sensitivity and overall health status in patients who underwent surgery for vestibular schwannoma and were prehabituated by chemical vestibular ablation.

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Key information

Conditions

Vestibular Schwannoma Cranial Nerve Diseases Cranial Nerve Neoplasms Ear Diseases Labyrinth Diseases Neoplasms Neoplasms by Histologic Type Neoplasms by Site Neoplasms, Germ Cell and Embryonal Neoplasms, Nerve Tissue Nerve Sheath Neoplasms Nervous System Diseases Nervous System Neoplasms Neurilemmoma Neuroectodermal Tumors Neuroendocrine Tumors Neuroma Neuroma, Acoustic Otorhinolaryngologic Diseases Otorhinolaryngologic Neoplasms Peripheral Nervous System Neoplasms Retrocochlear Diseases Vestibular Diseases Vestibular Function Disorder Vestibulocochlear Nerve Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Charles University

Prague, 150 06, Czechia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

T3, T4 vestibular schwannoma
recorded growth of a tumour
hearing loss greater than 50% in PTA

Exclusion criteria

T1 vestibular schwannomas
no growth progression
normal hearing

Treatment and study plan

intratympanic application of gentamicin

Procedure

under local anesthesia is gentamicin instilled through tympanic membrane to tympanic cavity

microsurgical removal of vestibular schwannoma

Procedure

surgery under general anesthesia

Primary outcomes

change of optokinetic nystagmus measurement

Time frame: change of the gain of optokinetic nystagmus among 3 time points is measured: before intervention, 1 week after intervention, 3 months after intervention

During electronystagmography gain of optokinetic nystagmus is measured before and after the intervention

Sponsors and collaborators

Lead sponsor

Charles University, Czech Republic

Other

Registry information

Official study title

Assessment of Visual Sensitivity, Psychiatric Profile and Quality of Life Following Vestibular Schwannoma Surgery in Patients Prehabituated by Chemical Vestibular Ablation

Important dates

Study start: 2016
Primary completion: 2018
Study completion: 2018
First posted: Aug 20, 2018
Registry last updated: Aug 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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