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NCT Number: NCT07138768

Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time in Emergency Settings

This study aims to evaluate the role of stroke protocol in the early diagnosis and management of acute stroke and its effect on turnaround time (TAT) in emergency settings.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location status: Recruiting

Location contact

Emad H Ali, MD

PRINCIPAL_INVESTIGATOR

Hala Desoky, MD

PRINCIPAL_INVESTIGATOR

Hend M Mansour, MD

CONTACT

[email protected]

00201221474344

Mohamed H Mattar, MD

PRINCIPAL_INVESTIGATOR

Radwa Mohamed, MD

PRINCIPAL_INVESTIGATOR

About this study

Acute stroke is a common and often devastating disorder; however, acute treatments that reduce long-term disability are available if patients present within the time window for treatment.

Computed tomography (CT) or magnetic resonance imaging (MRI) has been used in comprehensive stroke centers, although the role of advanced imaging in the improvement of stroke outcome remains controversial.

MRI offers advantages for the assessment of acute stroke. Changes of acute ischaemic injury are detectable sooner with MRI than with CT, especially with diffusion-weighted imaging, and ischaemic stroke diagnosis with MRI has greater interobserver and intraobserver reliability than CT, even in readers with little experience.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years.
  • Both sexes.
  • Patients with acute stroke who are admitted to the emergency department.

Exclusion criteria

  • Contraindications to magnetic resonance imaging (MRI) or computed tomography (CT).
  • Symptoms strongly suggestive of subarachnoid hemorrhage.
  • Initiation of antithrombotic or thrombolytic treatment before the completion of both scans.
  • Inability to complete both scans in time to allow thrombolytic treatment within three h of the onset of symptoms.
  • Uncontrollable hypertension.
  • Pregnant or lactating women.

Treatment and study plan

Magnetic Resonance Imaging

Device

Magnetic Resonance Imaging will be performed to all patients

Primary outcomes

  1. Sensitivity of magnetic resonance imaging for acute stroke

    Time frame: Immediately post-procedure (Up to 1 hour)

    Sensitivity of magnetic resonance imaging for acute stroke will be recorded.

Study contacts

Contact information is provided by the study sponsor or research team.

Hend M Mansour, MD

CONTACT

[email protected]

00201221474344

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

The Role of MRI in the Early Diagnosis and Management of Acute Stroke and Its Impact on Turnaround Time (TAT) in Emergency Settings

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 24, 2025
Registry last updated
Aug 26, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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