Aswan University
Aswān, 81528, Egypt
NCT Number: NCT03769818
The aim to study the efficacy of bupivacaine 0.25% with dexamethasone and that of bupivacaine 0.25% alone for erector spinae plane block for postoperative analgesia in patients undergoing total abdominal hysterectomy Group 1: bupivacaine 0.25% + dexamethasone 8 mg
* Group 2: bupivacaine 0.25% * Group3: control group A prospective Randomized Interventional double-blind study.
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Notify Me30 year–60 year
Female
Interventional
Not applicable
Aswān, 81528, Egypt
Optimal dynamic analgesia is recognized as the key to enhanced recovery following open abdominal surgery. In the last decade, there has been a significant shift away from thoracic epidural analgesia (TEA) that has been long considered as the gold standard. Various techniques have tried to replicate the analgesic efficacy of TEA. They include transversus abdominis plane analgesia (TAP), rectus sheath analgesia (RS), wound infusion analgesia (WI) and trans muscular quadratus lumborum analgesia. However, each of these techniques has specific limitations that prevent them from being the analgesic technique of choice for all open abdominal surgeries. Chin et al first described the erector spinae plane (ESP) block for providing analgesia following ventral hernia repair. The unique feature of the ultrasound-guided truncal blocks is that in all of these techniques, in contrast to peripheral nerve blocks, no nerve or plexus needs to be identified: Local anesthesia (LA) is injected in a particular muscle plane, in which the injectate spreads and reaches the intended nerves. This simple mechanism has made delivery of nerve blocks easy and versatile.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Bilateral TAP block with 20 ml of 0.25% bupivacaine
Other names: Active Comparator
Bilateral TAP block with 4 mg/kg dexamethasone diluted with isotonic saline.
Other names: active comparator
Bilateral TAP block with placebo to dexamethasone.
Bilateral TAP block with placebo to bupivacaine.
Time frame: 24 hours post operative
movement-evoked pain measurements ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 24 hours postoperative
ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 24 hours postoperative
calculation of the number of patients need Fentanyl consumption
Time frame: 4 weeks
calculation of number of days patients stay in hospital
Aswan University Hospital
Other
Role of Adjuvant Dexamethasone for Erector Spinae Plane Block for Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy: A Randomized, Double-blind Controlled Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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