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Completed

NCT Number: NCT06051708

Risk Factors And Outcomes Of Hospital Acquired AKI

The aim of the study is to assess the common risk factors for development of hospital acquired acute kidney injury among hospitalized patients in Alexandria Main University hospital and their outcomes.

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Key information

Conditions

AKI - Acute Kidney Injury Acute Kidney Injury Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine, Aexandria University

Alexandria, 21526, Egypt

About this study

Hospital-acquired AKI (HAAKI) is defined as acute renal insult occurring 48 hours or more after admission to a health care facility and It is estimated to occur in 13-18% of hospitalized patients. The early diagnosis of HAAKI reflects on improvement in morbidity and mortality rates especially in developing countries which goes parallel with the goal The International Society of Nephrology (ISN) to eliminate preventable or treatable deaths from AKI by 2025, the "0 by 25" initiative.

Data concerning the spectrum of acute kidney injury (AKI) in Egypt are generally scarce.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Fulfilment of definition of acute kidney injury according to KDIGO reference.
  • Age more than 18 years.

Exclusion criteria

  • Mentally or physically unfit patients.
  • Patients who developed acute kidney injury within 48 hours of admission to hospital.

Treatment and study plan

standard AKI care bundle

Other

AKI care bundle include use of iv fluids, diuretics, antihyperkalemic drugs, sodium bicarbonate, antibiotics in septic patients.

standard care for hospitalized patients

Other

this includes iv fluids, diuretics, antibiotics in septic patients, other measures according to original disease

Primary outcomes

  1. Recovery of kidney functions

    Time frame: 12 weeks

    (improvement of eGFR, serum creatinine to normal or previous baseline).

Secondary outcomes

  1. progression to chronic kidney disease.

    Time frame: 12 weeks

    deterioration of kidney functions ( creatinine, eGFR)

  2. mortality

    Time frame: 12 weeks

    death

  3. Need for renal replacement therapy

    Time frame: 12 weeks

    different modalities of RRT

Sponsors and collaborators

Lead sponsor

Alexandria University

Other

Registry information

Official study title

Risk Factors And Outcomes Of Hospital Acquired Acute Kidney Injury: A Tertiary Health Care Center Experience

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Sep 25, 2023
Registry last updated
Jun 18, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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