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Completed

NCT Number: NCT06526884

Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)

The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness. The way it does this is by identifying patients in the ED who would normally be admitted for low-acuity conditions, and diverting them to a high-acuity clinic the following day called the NDC. This will help decompress the ED and the hospital, and allow for overall higher quality care. The Health System has partnered with UCLA's Healthcare Value Analytics and Solutions [UVAS] group which specializes in these types of program evaluations. The analysis conducted by the study team will be used to directly inform NDC operations, scaling, and future plans.

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Key information

About this study

NDC is a hospital avoidance model with the potential to simultaneously improve the quality and safety of acute care, reduce costs, and address hospital/ED overcrowding. This novel hospital avoidance program will divert patients from the ED who have been diagnosed with the following conditions and meet certain clinical criteria:

  • Diabetic Foot Infection/Osteomyelitis
  • Cellulitis
  • Congestive Heart Failure
  • Syncope
  • Pyelonephritis/Urinary Tract Infection
  • Pneumonia
  • Acute Kidney Infection

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age or older
  • About to be admitted through the ED for one of the NDC diagnoses or a synonym (per Study Protocol document), defined by the presence of a Plan to Admit order or Bed Request order, OR recently admitted under observation or inpatient status for one of the NDC diagnoses.
  • Identified as at-risk for an avoidable hospitalization in the ED based on a pre-determined set of lab and vital parameters.
  • Insurance that authorizes the patient to follow-up at UCLA Health, or self-pay
  • Admitted or being admitted to an internal medicine service

Exclusion criteria

  • Heart or lung transplant recipient with concern for graft dysfunction
  • Pregnant
  • Enrolled in hospice
  • Admitted to a critical care service
  • ED deems discharge unsafe due to complex social or medical factors
  • Active malignant cancer (per Council of State and Territorial Epidemiologists value set)
  • Pulmonary arterial hypertension (per Joint Commission value set)
  • Undergoing workup for solid organ transplant
  • Interstitial lung disease (including pulmonary fibrosis) (per Higher Level 7 value set)
  • Requiring inpatient procedure or surgery defined by the presence of an anesthesia event or operating room encounter.
  • The ED deems discharge unsafe due to complex social or medical factors.
  • Transferred to an ineligible hospital

Note:

The Health System plans to limit the volume of referrals to the NDC by only referring patients who have an even birth date (this is more equitable than first-come-first-serve, because wage workers are more likely to come to the ED later in the day; even/odd birth date theoretically keeps more spots open for patients presenting to the ED later).

Treatment and study plan

Next Day Clinic

Other

A dedicated Next Day Clinic team consisting of a clinician and nurse case manager will provide care and specialist referrals to patients within 24 hours of an ED visit that would have resulted in hospitalization without this novel hospital avoidance initiative.

Primary outcomes

  1. Days alive and out of hospital (DAOH)

    Time frame: 30 days from index ED visit

    Cumulative number of days alive and not admitted or boarding in a hospital or emergency department

Secondary outcomes

  1. Global health-related quality of life

    Time frame: 30 days from index ED visit

    Composite PROMIS-29+2 score (patient reported outcome measurement information system). PROMIS stands for Patient-Reported Outcomes Measurement Information System. High scores mean more of the concept being measured.

  2. Patient experience

    Time frame: 30 days from index ED visit

    Measured by PSQ-18 (patient satisfaction questionnaire). PSQ stands for Patient Satisfaction Questionnaire. High scores indicate higher levels of satisfaction.

  3. Financial analysis

    Time frame: Through study completion, an average of 12 months

    Total cost per day of treatment

  4. Cost effectiveness analysis

    Time frame: Through study completion, an average of 12 months

    Total cost per day alive and out of hospital

  5. Hospitalizations avoided

    Time frame: Through study completion, an average of 12 months

    Each NDC referral with a preceding Plan to Admit order or Bed Request order (regardless of treatment arm) will be considered an avoided hospitalization, given that the presence of one of these orders establishes that the counterfactual for NDC treatment in hospitalization.

  6. Hospital bed-days saved

    Time frame: Through study completion, an average of 12 months

    For each referral to the NDC, the number of hospital bed-days saved will be established by using the mean length of stay for patients treated per-protocol in the control condition matched for the same presenting illness.

Sponsors and collaborators

Lead sponsor

University of California, Los Angeles

Other

Registry information

Acronym: NDC

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Jul 30, 2024
Registry last updated
May 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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