Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation

Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe .

a prospective study and retrospective part from hospital records.

Aim of the study:

1. Detect frequency, risk factors for development of biliary complications post living donor liver transplantation, types (stricture anastomotic or not, leak, biloma, stone, cholangitis etc.…). 2. Evaluate outcomes of different biliary complications

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Key information

Conditions

Liver Transplant; Complications

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Al-Rajhy liver hospital, Asyut, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt

Exclusion criteria

pediatric liver transplantation
cadaveric liver transplantation

Treatment and study plan

Primary outcomes

Incidence of biliary complications

Time frame: 1 year after liver transplantation

Biliary complications include biliary leak or stricture (anastomotic or non anastomotic), the investigator will record nature of complication , its time of presentation and number of hospital re-admissions due to biliary complications.
Type of intervention done to each complication

Time frame: 1 year after liver transplantation

Intervention is either non surgical (ERCP or PTD) or surgical revision with detailed description of each intervention and if the intervention is successful or not (biliary stricture resolved by MRCP, improvement of liver functions and symptoms)

Study contacts

Contact information is provided by the study sponsor or research team.

Sara Sedeek

CONTACT

[email protected]

+201022177340

Sponsors and collaborators

Lead sponsor

Assiut University

Other

Registry information

Official study title

Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation in Al-Rajhy Liver Hospital in Upper Egypt.

Important dates

Study start: 2024
Primary completion: 2027
Study completion: 2027
First posted: Dec 28, 2018
Registry last updated: Jul 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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