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NCT Number: NCT07715500

Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications

Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential

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Key information

Conditions

Chronic Liver Disease and Cirrhosis Donor Hepatectomy Fibrosis Liver Transplant; Complications Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All prospective voluntary healthy liver donor of age 18-55

Exclusion criteria

  • Type C/D Portal vein anatomy
  • Left sided Gallbladder
  • Right Posterior Graft
  • Recipients undergoing Hepaticojejunostomy

Treatment and study plan

Magnetic Resonance Cholangiopancreatography

Diagnostic Test

Magnetic Resonance Cholangiopancreatography is being excluded from list of Investigation as part of Non inferiority trial

Primary outcomes

  1. To identify factors causing early biliary complications like type and number of arterial & biliary reconstruction, type of graft, number & size of Bile ducts in donor in both groups

    Time frame: 6 month of postop

Secondary outcomes

  1. Donor biliary complications in both group

    Time frame: 1 month of postoperative period

    Bile leak or strictures in Liver Donors

  2. Identify Risk factors for early Biliary complications in recipients

    Time frame: till 6 months of Post operative period of Liver transplant

    Identify Risk factors for early Biliary complications in recipients

Study contacts

Contact information is provided by the study sponsor or research team.

Dr Atul Renjit, MBBS, MS, DNB

CONTACT

[email protected]

+91 9632060230

Dr Nilesh Sadashiv Patil, MCH

CONTACT

Sponsors and collaborators

Lead sponsor

Institute of Liver and Biliary Sciences, India

Other

Registry information

Official study title

Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications - Open Label Randomised Controlled Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 20, 2026
Registry last updated
Jul 20, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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