Retinal Oxygen Metabolism in Children With Myopia

Inclusion criteria

for children with myopia:

• Children aged between 8 and 13 years (inclusive)
• Signed informed consent of child and legal guardian
• Normal ophthalmic findings except myopia
• Cycloplegic spherical equivalent (SE) refraction ≤ -1.0dpt in both eyes
• Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant

Inclusion criteria

for healthy age- and sex-matched controls:

• Children aged between 8 and 13 years (inclusive)
• Signed informed consent of child and legal guardian
• Normal ophthalmic findings
• Cycloplegic spherical equivalent (SE) refraction between +0.5dpt and -0.5dpt
• Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant

Exclusion criteria

• Intake of stimulating beverages containing xanthine derivatives (tea, coffee, cola-like drinks) 12 hours before the study day
• Previous eye abnormalities such as cataract, keratopathy, strabismus, amblyopia, ocular inflammation, trauma, or surgery
• History of any disease or syndrome associated with severe myopia such as Marfan syndrome, Stickler syndrome, or retinopathy of prematurity
• Non-axial cause of myopia
• BCVA less than 20/25
• Intraocular pressure ≥ 21mmHg
• Astigmatism ≤ -1.0dpt
• Anisometropia ≥ 2dpt
• Not able to read letters for visual acuity testing