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OpenTrials
Not Yet Recruiting

NCT Number: NCT06846151

Retinal Investigation Using Optos OCT Device

Retinal investigation using OCT with control and diseased eyes

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Trial opening soon.

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Key information

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female participants 18 years of age or older who have full legal capacity to volunteer on the date the informed consent is signed.
  • Participants who understand the study and patient information sheet and can follow the instructions.
  • Participants who agree to participate in the study.
  • Control group where no retinal abnormalities were detected as part of the standard basic ophthalmic examination.
  • Participants with retinal disease in at least one eye including: Early dry age-related macular degeneration, late stage dry age-related macular degeneration specifically geographic atrophy, Wet age-related macular degeneration, Retinitis pigmentosa, Diabetic retinopathy and other macular atrophic diseases

Exclusion criteria

  • Inability to understand written and verbal English sufficiently to comprehend the study and provide informed consent
  • Ophthalmic disease other than condition under investigation.
  • Participants unable to tolerate ophthalmic imaging.
  • Cataract (unless deemed mild in the opinion of the investigator)
  • Participants with significant ocular media not sufficiently clear to obtain acceptable OCT images.
  • Diabetes (unless part of the diabetic eye disease group)
  • Binocular visual acuity worse than 6/18
  • Strabismus (squint)
  • Age related macular degeneration groups: polypoidal choroidal vasculopathy
  • Participants with photo sensitivity epilepsy, experience of seizures, or sensitivity to flickering light (based on self-report)
  • Pregnant

Treatment and study plan

retinal functional imaging

Device

this is a proof of concept study

Other names: OCT

Primary outcomes

  1. OCT physical response data

    Time frame: 6 months from recruitment start

    Response data per participant will be collected and analyzed

Sponsors and collaborators

Lead sponsor

Optos, PLC

Industry

Registry information

Official study title

Clinical Investigation of Optos OCT in Patients with Retinal Pathologies

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Feb 25, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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