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OpenTrials
Completed

NCT Number: NCT06269003

Responses to Message Source and Presentation Using Psychophysiology

The goal of this clinical trial is to use psychophysiological methods to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for young adults who vape and do not vape.

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Key information

Conditions

Age range

18 year–24 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UMass Chan Medical School Shaw Building

Worcester, Massachusetts, 01605, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ages 18-24
  • Fluent in English
  • Either vaping in the past 30 days or not having vaped in the past 30 days but susceptible to vaping
  • Self-reported abstinence of combusted tobacco or marijuana at time of visit

Exclusion criteria

  • Ages below 18 or above 24
  • Not fluent in English
  • Not confirmed self-reported abstinence of combusted tobacco or marijuana at time of visit

Treatment and study plan

Expert, one-sided

Other

Participants will view a brief description of an expert source and see one-sided e-cigarette education messages.

Expert, two-sided

Other

Participants will view a brief description of an expert source and see two-sided e-cigarette education messages.

Peer, one-sided

Other

Participants will view a brief description of a peer source and see one-sided e-cigarette education messages.

Peer, two-sided

Other

Participants will view a brief description of a peer source and see two-sided e-cigarette education messages.

Primary outcomes

  1. Visual Attention

    Time frame: The entire duration of message from beginning of its delivery to the completion of viewing, up to 45 minutes.

    Visual attention was assessed by measuring dwell time, which is the length of time participants spent on looking at the specific areas of interest (AOIs) collected in miliseconds. Dwell time values were collected for 18 messages, and aggregated to provide the average dwell time scores for each arm. This was done for each vaping status (current vapers and susceptible non-vapers). Higher dwell time scores indicate higher visual attention, indicating better message outcomes.

  2. Allocation of Cognitive Resources

    Time frame: Baseline and immediately after viewing all the messages (approximately 45 minutes).

    Heart rate values were collected in beats per minute (BPM) on a per-second basis during the presentation of each 18 distinct messages as well as during the immediately preceding black screen (baseline) for each message. Descriptive statistics were used to summarize changes in the BPM values during the message exposure period by comparing the BPM values collected during each message second to the BPM values collected during the immediately preceding baseline period. These change scores were then averaged across all messages within each study arm to generate a mean BPM value per condition, and this was done for each vaping status (current vapers and susceptible non-vapers). Lower BPM values reflect greater cognitive response, therefore indicate better message outcomes.

  3. Arousal

    Time frame: Baseline and immediately after viewing all the messages (approximately 45 minutes).

    Galvanic Skin Response (GSR) values were recorded in microsiemens on a per-second basis during the presentation of each 18 distinct messages as well as during the immediately preceding black screen (baseline) for each message. Descriptive statistics were used to summarize changes in GSR values by comparing each message response to its preceding baseline period. These change scores were then averaged across all messages within each study arm to generate a mean GSR score per condition, and this was done for each vaping status group (current vapers and susceptible non-vapers). Higher GSR values reflect greater physiological arousal, and indicate better message outcomes.

Secondary outcomes

  1. Attitudes

    Time frame: After exposure to all messages, approximately up to 45 minutes.

    Participants' self-reported vaping attitudes were measured by using a five-point bipolar scale using 7 subscale items assessing whether participants thought vaping was enjoyable, healthy, safe, fun, smart, cool, and attractive on a scale from 1 (negative attitudes) to 5 (positive attitudes). Items were summed and averaged to create a single composite score, and this was done for each arm for each vaping status. Higher scores indicate more positive e-cigarette attitudes, therefore worse outcomes.

  2. Behavioral Intentions

    Time frame: After exposure to all messages, approximately up to 45 minutes.

    Participants' vaping intentions was measured by using a 3 subscale items assessing participants' intentions to vape: soon/anytime during the next year/would use offered by one of their best friends, on a scale from 1 (Definitely not) to 5 (Definitely yes). Items were summed and averaged to create a single composite score. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater vaping intentions, therefore indicating worse outcome.

Sponsors and collaborators

Lead sponsor

University of Massachusetts, Worcester

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-vapers - Part 2

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Feb 21, 2024
Registry last updated
Aug 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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