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Completed

NCT Number: NCT07116837

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

The purpose of the Aim 2 study is to assess the perceived effectiveness of vaping prevention ads among adolescents and young adults and identify which features of video ads predict perceived message effectiveness. Participants will include adolescents aged 13-17 and young adults aged 18-20 who live in the US and who are susceptible to vaping or who currently vape. In an online survey, participants will be randomized to view five randomly selected vaping prevention ads identified from a previous content analysis. After viewing the videos, participants will rate each video on the perceived message effectiveness scale and respond to questions about vaping appeal and urge to vape. The survey will take 15-20 minutes.

A follow-up survey of a subset of participants will be conducted around two weeks after they have been exposed to vaping prevention video ads in the baseline survey. Participants will view a total of six videos, including the five videos they watched previously, shown one at a time, along with one "decoy" video ad. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The survey will take 10-15 minutes.

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Key information

Conditions

Age range

13 year–20 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of North Carolina, Chapel Hill

Chapel Hill, North Carolina, 27599, United States

About this study

Health communication campaigns are a scientific approach for preventing and reducing tobacco product use among adolescents. Although a growing number of studies have examined the effects of e-cigarette communication among young adults, there is only a modest number of published studies targeting adolescents. There is little information about the objective features of vaping prevention video ads. Additionally, the follow-up study will explore how ad features are associated with recognition.

Setting: This study is an online survey of adolescents and young adults (age 13-20) who are susceptible to vaping or who currently vape and live in the United States.

Recruitment and Informed Consent: Adolescent and young adult participants will be recruited by Qualtrics Services. Participants who are 18 to 20 years old and are eligible for the study will view a consent form as part of the survey and check a box to indicate that they agree to participate in the study. For minor participants, Qualtrics will recruit parents of 13-17-year-olds, so they will receive the survey invitation with the parental permission/consent form. From there, parents will be asked to pass the survey to their child. Once the participant has completed the consent/assent process, they will be able to begin the survey.

Procedures: up to 3,500 adolescents and young adults who are susceptible to vaping or currently vape will be randomized to view 5 randomly selected ads from a pool of vaping prevention video ads identified from previous study activities. Participants will be screened for susceptibility to vaping or current vape use. Participants will then answer questions on demographic information and tobacco product use. They will view 5 videos, 1 at a time ,randomly assigned from the larger pool of videos. After viewing the videos, participants will rate each video on perceived message effectiveness (primary outcome) and respond to questions about vaping appeal and urge to vape (secondary outcomes). Finally, participants will respond to standard questions on psychological distress, tobacco product use in the home, and general health-related questions. After the survey, participants will view a debrief page with information about tobacco use harms. The survey will take 15-20 minutes.

For the follow-up study, a subset of participants will be asked to complete another survey around two weeks after they have been exposed to vaping prevention video ads in the first survey. In this survey, participants will view a total of six videos, including the five videos they watched when taking the Aim 2 survey around two weeks earlier, shown one at a time, along with one "decoy" video ad. The order of the videos will be randomized. After watching each video ad, participants will indicate whether they remember seeing the ad in the survey they took around two weeks prior. The follow-up survey will take 10-15 minutes.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 13-20 years old
  • Current vaper (defined as using e-cigarettes in the past 30 days) or susceptible to vaping. Participants will be considered 'susceptible to vaping' if they answer anything other than "definitely not" to 3 screening items assessing their susceptibility to vaping. An example item is, "If one of your best friends were to offer you a vape, would you use it?" (Definitely not, probably not, probably yes, definitely yes).
  • Live in the United States

Exclusion criteria

  • Live outside of the United States

Treatment and study plan

Vaping prevention video ads

Behavioral

Participants will view and rate 5 vaping prevention video ads. The vaping prevention video ads cover a variety of different topics and were identified in a previous study activity.

Primary outcomes

  1. Perceived Message Effectiveness

    Time frame: Baseline (Main study)

    The 3-item perceived message effectiveness scale assesses the extent to which participants perceived the vaping prevention video ads as effective. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". The overall scale score is determined by averaging scores from the 3 items, with higher scores representing higher perceived message effectiveness. This is the primary outcome for the main study.

  2. Recognition

    Time frame: Two-week Follow-up

    This survey item assesses whether the participant remembers viewing the ad in the baseline survey 2 weeks prior. Response options are "Yes", "No", and "Not sure". The response will be dichotomized as 1 = "Yes" and 0 = "No"/"Not sure" for analyses. This is the primary outcome for the follow-up study.

Secondary outcomes

  1. Urge to vape

    Time frame: Baseline

    This survey item assesses the extent to which the video ad makes participants want to vape. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". A higher score represents a stronger urge to vape. This is a secondary outcome of the main study.

  2. Vaping appeal

    Time frame: Baseline

    This survey item assesses the extent to which the ad makes vaping seem appealing. Response options are on a 5-point scale from 1="Not at all" to 5="A great deal". A higher score represents higher vaping appeal. This is a secondary outcome of the main study.

Sponsors and collaborators

Lead sponsor

UNC Lineberger Comprehensive Cancer Center

Other

Collaborators

  • Food and Drug Administration (FDA)
  • National Institute on Drug Abuse (NIDA)

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Aug 12, 2025
Registry last updated
Jul 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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