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OpenTrials
Completed

NCT Number: NCT06274723

Responses to E-cigarette Message Source and Presentation

The goal of this clinical trial is to use crowdsourcing to test the effects of a message source (expert and peer) and message presentation types (one-sided and two-sided) to identify the optimal message type for young adults who vape and do not vape.

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Key information

Conditions

Age range

18 year–24 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

UMass Chan Medical School

Worcester, Massachusetts, 01605, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • US residents ages 18-24
  • Fluent in English
  • Reporting either vaping in the past 30 days or not having vaped in the past 30 days but susceptible to vaping

Exclusion criteria

  • Age less than 18 or above 24
  • Not fluent in English
  • Not a member of partnering crowdsourcing behavioral research platform conducting the study

Treatment and study plan

Expert, one-sided

Other

Participants will view a brief description of an expert source and see one-sided e-cigarette education messages.

Expert, two-sided

Other

Participants will view a brief description of an expert source and see two-sided e-cigarette education messages.

Peer, one-sided

Other

Participants will view a brief description of a peer source and see one-sided e-cigarette education messages.

Peer, two-sided

Other

Participants will view a brief description of a peer source and see two-sided e-cigarette education messages.

Primary outcomes

  1. Message Acceptance

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Participants' self-reported message acceptance were measured by using a five-point Likert scale using five items assessing whether participants thought the message was worth remembering, grabbed their attention, powerful, convincing, and meaningful on a scale from 1 (Strongly disagree) to 5 (Strongly agree). Items were summed and averaged to create a single composite score, and this was done for each arm for each vaping status. Higher scores indicate more more message acceptance, therefore better outcomes.

  2. Harm Perceptions

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Harm perceptions was measured by a single item e-cigarette harm perceptions question assessing participants' perceived absolute harm of e-cigarette use on a scale from 1 (Not at all harmful) to 10 (Very harmful). Items were summed and averaged to create a single composite score. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater vaping harm perceptions, therefore indicating better outcome.

Secondary outcomes

  1. Negative Cognition

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Negative cognition was measured by six-item reactance questionnaire, such as perceptions of messages being manipulative, misleading, distorted, overblown, exaggerated, and overstated on a scale from 1 (Strongly disagree) to 5 (Strongly agree). Higher scores indicate greater negative cognition, indicating worse outcome.

  2. Message Anger

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Message anger was measured by four item message anger question assessing the extent to which the messages made participants feel irritated, angry, annoyed, and aggravated on a scale from 1 (not at all) to 5 (very much). Items were summed and averaged. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater anger toward messages, indicating worse outcomes.

  3. Message Liking

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Message liking will be measured by a single-item liking of the message on scale from 1 (Dislike very much) to 5 (Like very much). Items were summed and averaged to create a single composite score. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater message liking, therefore indicating better outcome.

  4. Source Trust

    Time frame: After exposure to each messages (approximately up to 20 minutes total), measured during a single study visit on Day 1.

    Source trust was measured by a single-item trust in health information source questionnaire, such as trust in source about vaping information on a scale from 1(Not at all) to 5 (Very much so). Items were summed and averaged to create a single composite score. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater source trust, therefore indicating better outcome

  5. Attitudes

    Time frame: After exposure to all messages (approximately up to 45 minutes), measured during a single study visit on Day 1.

    Participants' self-reported vaping attitudes were measured by using a five-point bipolar scale using 7 subscale items assessing whether participants thought vaping was enjoyable, healthy, safe, fun, smart, cool, and attractive on a scale from 1 (negative attitudes) to 5 (positive attitudes). Items were summed and averaged to create a single composite score, and this was done for each arm for each vaping status. Higher scores indicate more positive e-cigarette attitudes, therefore worse outcomes.

  6. Behavioral Intentions to Vape or Try Vaping

    Time frame: After exposure to all messages (approximately up to 45 minutes), measured during a single study visit on Day 1.

    Participants' vaping or vaping trial intentions were measured by using a 3 subscale items assessing participants' intentions to vape: soon/anytime during the next year/would use offered by one of their best friends, on a scale from 1 (Definitely not) to 5 (Definitely yes). Items were summed and averaged to create a single composite score. This was done for each vaping status (current vapers and susceptible non-vapers). Higher scores indicate greater vaping intentions, therefore indicating worse outcome.

Sponsors and collaborators

Lead sponsor

University of Massachusetts, Worcester

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-vapers - Part 1

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Feb 23, 2024
Registry last updated
Jan 14, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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