Pediatric dentistry and Public health department-Cairo University
Cairo, Egypt
NCT Number: NCT02943759
The trial is to test the resolution of pain, swelling and other signs of periapical infection and the antimicrobial efficacy when using the neem leaf extract compared to chlorhexidine as root canal irrigant in Pulpectomy treatment for children.
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Notify Me4 year–8 year
All sexes
Interventional
Phase 2 / Phase 3
Cairo, Egypt
To compare the effectiveness of neem leaf extract with that of Chlorhexidine gluconate when used as an intracanal irrigant in primary molar teeth indicated for pulpectomy treatment.
P: children with primary necrotic molars indicated for pulpectomy I: Neem leaf extract (alcoholic solution). C: 2% chlorhexidine gluconate. O: Pain and swelling resolution. T:Over 12 months. S: Randomised controlled trial.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
A natural irrigant solution act as anti-inflammatory and anti bacterial
2%chlorhexidine gluconate , anti bacterial root canal irrigant solution
Other names: Gluconate-Chex 2%
Time frame: 1 year
Patient reported pain and pain on percussion , binary
Time frame: 1 year
Visual examination ,binary
Time frame: 1 year
Mobility test ,binary
Time frame: 48 hours
Bacteria on culture plates measuring unit CFU/ml
Time frame: 1 year
Periapical radiograph , binary
Cairo University
Other
Resolution of Pain and Swelling After the Use of Neem Leaf Extract (Azadirachta Indica) Compared to Chlorhexidine Gluconate as an Intracanal Irrigant in Necrotic Primary Molar Teeth in Children Undergoing Pulpectomy Treatment: A Randomised Controlled Trial
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