Root Canal Treatment Outcome in Patients Under Bisphosphonate Therapy

The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy . Clinical complications, success and survival rate was reported. Mean clinical parameters, clinical symptoms and presence of periapical radilucency were recorded.

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Key information

Conditions

Root Canal Infection Abscess Bisphosphonate-Associated Osteonecrosis Bisphosphonate-Associated Osteonecrosis of the Jaw Bone Diseases Dental Pulp Diseases Endodontically Treated Teeth Infections Jaw Diseases Mouth Diseases Musculoskeletal Diseases Necrosis Osteonecrosis Pathologic Processes Pathological Conditions, Signs and Symptoms Periapical Abscess Periapical Diseases Periapical Periodontitis Periodontal Diseases Periodontitis Stomatognathic Diseases Suppuration Tooth Diseases Tooth, Nonvital

Age range

40 year–85 year

Sex eligibility

All sexes

Study type

Observational

About this study

The study was conducted in one University Endodontic Clinical Department - Dental School between January 2009 and December 2017.

Root canal treatment was performed according previously reported operative protocols.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients affected by endodontic disease and able to attend a hygiene recall program

Exclusion criteria

inability to attend a recall hygien program

Treatment and study plan

Root canal treatment

Procedure

Root canal treatment using a standard manual k file instrumentation and carrier-based root canal filling technique

Primary outcomes

health patients

Time frame: 5 years

assessment of periapical index (PAI)

Secondary outcomes

Complications

Time frame: 5 years

extraction periapical re exacerbation during before the endline ( 5 years)

Sponsors and collaborators

Lead sponsor

University of Bologna

Other

Registry information

Official study title

Root Canal Treatment of Compromised Teeth as Alternative Treatment in Patients Under Bisphosphonate Therapy: 60-month Results of a Prospective Clinical Study

Important dates

Study start: 2009
Primary completion: 2016
Study completion: 2017
First posted: May 22, 2020
Registry last updated: May 27, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed