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Completed

NCT Number: NCT00033033

Reserpine for the Treatment of Cocaine Dependence - 1

The purpose of this study is to assess the efficacy and safety of reserpine for the treatment of cocaine dependence.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Substance-Related Disorders

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Boston University Medical Center, Boston, Massachusetts, United States

Loading trial locations.

About this study

To assess the efficacy and safety of reserpine in reducing cocaine use in subjects with cocaine dependence. This is a double-blind, placebo-controlled, parallel-group design with a 2 week baseline period.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Be at least 18 yrs of age; DSM-4 diagnosis of cocaine dependence; treatment seeking individuals; have the ability to understand and provide written informed consent; females of child bearing potential using appropriate birth control method

Exclusion criteria

Additional criteria available during screening at the site.

Treatment and study plan

reserpine

Drug

Primary outcomes

  1. Cocaine use

  2. Addiction severity

  3. Cocaine withdrawal

  4. Adverse events

  5. Clinical improvement

Sponsors and collaborators

Lead sponsor

National Institute on Drug Abuse (NIDA)

Nih

Collaborators

  • Cincinnati VA Medical Center

Registry information

Official study title

Phase 2, Double-Blind, Placebo-Controlled Trial of Reserpine for the Treatment of Cocaine Dependence

Important dates

Study start
2001
Study completion
2003
First posted
Apr 8, 2002
Registry last updated
Jan 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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