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OpenTrials
Completed

NCT Number: NCT00000311

Combining Behavioral Treatment With Agonist Maintenance - 1

The purpose of this study is to evaluate whether the community reinforcement approach (CRA) plus contingency management (CM) is more effective overall than CRA only in reducing illicit opioid and cocaine use during agonist maintenance treatment and at 3 and 6 month follow-up after completion of study protocol, and to compare the efficacy of maintenance on buprenorphine to methadone when maintenance is combined with CRA only or CRA plus CM.

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Key information

Conditions

Cocaine-Related Disorders Chemically-Induced Disorders Mental Disorders Narcotic-Related Disorders Opioid-Related Disorders Substance-Related Disorders

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

APT Residential Services Division

New Haven, Connecticut, 06519, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Please contact site for information.

Treatment and study plan

buprenorphine

Drug

Medication and Behavioral

Methadone

Drug

medication and behavioral

Primary outcomes

  1. Depression

    Time frame: 24 weeks

  2. Withdrawal symptoms

  3. Opioid and cocaine use

  4. Social and psychological functioning

  5. AIDS risk behavior

Sponsors and collaborators

Lead sponsor

Yale University

Other

Collaborators

  • National Institute on Drug Abuse (NIDA)

Registry information

Official study title

Combining Behavioral Treatment With Agonist Maintenance

Important dates

Study start
1995
Primary completion
1999
Study completion
1999
First posted
Sep 21, 1999
Registry last updated
Jan 17, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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