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Completed

NCT Number: NCT07170774

Research on the Enhancement of Aerobic Metabolic Energy Supply Capacity by Ischemic Preconditioning.

The purpose of this clinical trial is to investigate whether IPC can improve aerobic capacity during exercise. The primary question it aims to answer is: Does IPC enhance the aerobic capacity of athletes? The researchers will compare IPC (220 mmHg pressure) with a placebo (20 mmHg pressure) to see if different interventions can enhance aerobic capacity and exercise performance.

Participants will:

* Undergo a randomized crossover controlled trial, visiting twice, with a one-week interval between each test. * Conduct two assessments at the testing site each time, namely a pre-intervention assessment and a post-intervention assessment. * Record their heart rate, blood pressure, weight, oxygen uptake, Taekwondo-specific performance, and other indicators.

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Key information

Conditions

Ischemic Preconditioning Aerobic Capacity

Age range

18 year–22 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Guangzhou Sport University

Guangzhou, 510500, China

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adult male athletes aged 18 years or older;
  • taekwondo athletes classified as national second-class or above (having placed in the top three provincial professional taekwondo championships or the top eight national professional taekwondo championships);
  • consistent and unified training over the past three months;
  • no prior ischemic preconditioning;
  • competitive taekwondo athletes.

Exclusion criteria

  • supplementation with creatine;
  • acute or chronic illnesses, including anxiety, depression, cardiovascular diseases, and metabolic disorders;
  • engaging in vigorous physical activity within 48 hours prior to the experiment;
  • consuming alcohol or caffeine within 24 hours before the experiment.

Treatment and study plan

Ischemic Preconditioning

Device

Compression cuff width: 10CM; Compression duration: 5min/5min (ischemia/reperfusion) *4. 220 mmHg

SHAM

Device

Compression cuff width: 10CM; Compression duration: 5min/5min (compression/relaxation) *4. 20 mmHg

Primary outcomes

  1. Oxygen uptake

    Time frame: Participants had their oxygen uptake measured continuously during both visits, extending until six minutes after the completion of the exercise test.

    To record the oxygen uptake of the subjects and compare the changes in oxygen uptake after the intervention.

  2. Taekwondo-specific sports performance test

    Time frame: The subjects rested quietly for five minutes before baseline measurements were taken. After this, the collection of metabolic gases commenced. Throughout the experiment, metabolic gases were continuously collected until six minutes after the tests.

    The specialized athletic ability in Taekwondo is measured by the number of kicks performed during the test.

  3. Blood lactate

    Time frame: Blood lactate levels were measured at baseline, immediately after the intervention at 3 minutes, and at 3 and 10 minutes post-testing.

    Used to measure the intensity and metabolic adaptations during the testing process of taekwondo athletes

Sponsors and collaborators

Lead sponsor

Ziyue Ou

Other

Registry information

Official study title

Ischemic Preconditioning Enhances Aerobic Metabolic Energy Supply Capacity During Frequency Speed of Kick Test in Taekwondo Athletes: A Randomized Crossover Study

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Sep 12, 2025
Registry last updated
Sep 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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