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OpenTrials
Completed

NCT Number: NCT02201797

Reproducibility and Repeatability of Multifunctional MRI Biomarkers of the Body

Advanced MRI (Magnetic Resonance Imaging) technique called DCE (Dynamic Contrast Enhanced) and DWI MRI can provide valuable information regarding tumor biology and response to treatment through various parameters. Validating stability of these parameters will further establish robustness and reliability of these promising biomarkers.

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Key information

Conditions

Metastatic Liver Cancer Digestive System Diseases Digestive System Neoplasms Liver Diseases Liver Neoplasms Neoplasm Metastasis Neoplasms Neoplasms by Site Neoplastic Processes Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Asan Medical Center

Seoul, 138-736, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosis of metastatic liver cancer proven by pathology
  • At least one liver tumor should be > 2cm in long diameter
  • Patients with viable tumor proven in the other imaging modalities

Exclusion criteria

  • Severe claustrophobia
  • Presence of MRI-incompatible metallic objects or implanted medical devices in body
  • Renal failure, as determined by glomerular filtration rate (GFR) < 30 mL/min/1.73 m2
  • Weight greater than that allowable by the MRI table
  • Chemotherapy within 28 days prior to enrollment
  • Prior external radiation therapy to the liver, prior transarterial chemoembolization

Treatment and study plan

DCE MRI

Other

Primary outcomes

  1. repeatability coefficient (RC)

    Time frame: one year

    Repeatability coefficient of Ktrans, Kep, Ve, IAUGC60, and ADC value of the index tumor will be measured.

Sponsors and collaborators

Lead sponsor

Asan Medical Center

Other

Collaborators

  • Bracco Diagnostics, Inc

Registry information

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Jul 28, 2014
Registry last updated
Jun 24, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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