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Completed

NCT Number: NCT01128933

Renal Fractional Flow Reserve in Renal Artery Stenting

The purpose of the study is to determine potential utility of renal fractional flow reserve in prognosis predicting after renal stent implantation.

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Key information

Conditions

Renal Artery Stenosis Arterial Occlusive Diseases Cardiovascular Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Hypertension Kidney Diseases Male Urogenital Diseases Renal Artery Obstruction Urogenital Diseases Urologic Diseases Vascular Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Institute of Cardiology

Warsaw, 04-628, Poland

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • At least moderate (60% or more) renal artery stenosis with atheromatic appearance in angiography
  • Hypertension defined according to WHO criteria
  • Age 18-75 years
  • Signed informed consent obtained

Exclusion criteria

  • Bilateral renal artery stenosis or significant renal artery stenosis in solitary kidney
  • Contraindications to percutaneous renal angioplasty with stenting
  • Atrophy of the kidney supplied with stenosed artery
  • Other well known secondary reason for hypertension
  • Chronic heart failure NYHA II-IV
  • Significant valvular heart disease qualified for surgery
  • Persistent atrial fibrillation
  • Renal failure with GFR below 30ml/min

Treatment and study plan

Renal artery stenting

Procedure

Primary outcomes

  1. Blood pressure improvement

    Time frame: 6 months

Secondary outcomes

  1. Kidney function preservation

    Time frame: 6 months

Sponsors and collaborators

Lead sponsor

National Institute of Cardiology, Warsaw, Poland

Other

Collaborators

  • Ministry of Science and Higher Education, Poland

Registry information

Official study title

Prognostic Value of Renal Fractional Flow Reserve in Hypertensive Patients With Renal Artery Stenosis Qualified to Renal Artery Stenting

Acronym: PREFFER

Important dates

Study start
2006
Primary completion
2009
Study completion
2010
First posted
May 24, 2010
Registry last updated
May 24, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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