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OpenTrials
Completed

NCT Number: NCT06767202

Relationship Between Exposure to Phenols and Pregnancy Outcomes After Embryo Transfer

The goal of this observational study is to explore the association between phenol exposure and pregnancy outcome after embryo transfer. The main question it aims to answer [is/are]:

Whether exposure to phenols is associated with adverse pregnancy outcomes in pregnant women undergoing assisted reproductive technology?

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Key information

Conditions

Age range

20 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Reproductive center,tongji hospital,huazhong university of science and technology

Wuhan, Hubei, 430030, China

About this study

First of all, paper questionnaires were used in this study, including general information questionnaire, health effect questionnaire, health survey summary form, and dietary assessment questionnaire. Secondly, obtain the relevant information of the medical record system, including: assisted reproduction protocol, IVF examination results, B-ultrasound examination results, laboratory test indicators, pregnancy outcome information and newborn information. Finally, urine samples were detected using a high performance liquid chromatography mass spectrometer.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chinese citizens over the age of 20;
  • IVF/ICSI assisted reproductive treatment in our center;
  • Complete clinical data, reproductive outcomes and questionnaire data of both sexes;
  • Knowing about this research and voluntarily accepting this research;

Exclusion criteria

  • The patient receives sperm or egg donation treatment;
  • The patient gave up the egg collection operation due to various reasons, and the cycle was canceled;
  • The patient abandons treatment before achieving clinical pregnancy, but the fertile frozen embryo is not transferred;
  • There are contraindications to pregnancy, such as serious liver and kidney diseases, malignant tumors, serious mental diseases, uncorrected coagulation function abnormalities or endocrine indicators abnormalities;
  • Incomplete or missing clinical data or follow-up data;

Treatment and study plan

Primary outcomes

  1. Rate of clinical pregnancy patients

    Time frame: From the date of randomization until the termination of pregnancy

    Rate of biochemical pregnancy, clinical pregnancy and post-natal patients

Secondary outcomes

  1. Rate of the health newborn

    Time frame: From the date of randomization until the termination of pregnancy

    gestational age/preterm birth, physical health at birth, the incidence of systemic abnormalities or diseases, and other health outcomes

Sponsors and collaborators

Lead sponsor

keqin liu

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 9, 2025
Registry last updated
Jul 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.