Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer

The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques.

The secondary end points include the evaluation of the difficult transfer rates.

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Key information

Conditions

Fertility Issues Embryo Transfer Genital Diseases IVF Infertility Urogenital Diseases

Age range

18 year–43 year

Sex eligibility

Female

Study type

Observational

About this study

The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols.

Any blastocysts that underwent preimplantation genetic testing will be excluded from the analysis, as well as embryos derived from gamete donation or those imported from other centers.

Data are gathered using a specific internal web-based database, which allows to organize, store and readily retrieve information about patients and IVF cycle.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

IVF procedure
Fresh and frozen single blastocyst transfer

Exclusion criteria

Any blastocysts that underwent PGS testing
Embryos derived from gamete donation
Embryos imported from other centers

Treatment and study plan

Primary outcomes

clinical pregnancy rate

Time frame: 6 years

number of pregnancies diagnosed by ultrasonographic visualization of one or more gestational sacs x 100 divided by the number of embryo transfer cycles

Secondary outcomes

difficult transfer rate

Time frame: 6 years

advancement of the outer sheath, multiple attempts, force, required manipulation, use of a stylet or tenaculum, dilatation, use of a different catheter

Sponsors and collaborators

Lead sponsor

Istituto Clinico Humanitas

Other

Registry information

Official study title

Pregnancy Rate in Single Step Versus After Load Technique of Embryo Transfer: a Retrospective Analysis

Important dates

Study start: 2016
Primary completion: 2021
Study completion: 2021
First posted: May 6, 2022
Registry last updated: May 24, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed