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NCT Number: NCT07578090

Regional Innovation in Chronic Disease and Elderly Care

This project aims to develop a community-based health promotion intervention model for populations at potential risk of metabolic syndrome. Through exercise training and lifestyle modifications, the project seeks to improve cardiopulmonary function and disease control, align with current public health policies, and establish an evidence-based model with strong potential for broader implementation.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Fu Jen Catholic University Hospital, Fu Jen Catholic University

New Taipei City, 24352, Taiwan

Location status: Recruiting

Location contact

Ke-Yun Chao, PhD

CONTACT

[email protected]

+886-905-301-879

About this study

Background: Hypertension, diabetes, and dyslipidemia are major risk factors for cardiovascular disease, with prevalence continuing to rise in Taiwan. These conditions are closely associated with shared risk factors such as aging, obesity, and smoking. The districts of Xinzhuang, Wugu, and Taishan in New Taipei City are densely populated and have a significant aging population. Environmental changes such as urbanization and air pollution pose threats to residents' cardiopulmonary health. Exercise interventions have been proven effective in improving blood pressure, blood glucose, and lipid profiles, as well as enhancing cardiopulmonary function and quality of life. Therefore, implementing structured and personalized exercise promotion programs in the community is of great importance for disease control and health promotion among populations with metabolic syndrome.

Methods: Participants will first undergo a one-month in-hospital conventional exercise training program, followed by an eleven-month home-based exercise intervention. During and after the intervention period, physical activity assessments and biochemical blood tests will be conducted.

Effect: This project aims to establish a community-based health promotion model for individuals at risk of hypertension, diabetes, and hyperlipidemia, centered on exercise interventions and lifestyle modifications. Through assessment, stratification, intervention, and outcome tracking, the project seeks to enhance health behaviors, self-management skills, and cardiopulmonary function in at-risk populations, thereby slowing disease progression and reducing healthcare resource utilization. The research findings will be submitted to relevant domestic and international academic conferences and SCI journals to increase Taiwan's international visibility in the fields of geriatric and "three highs" care. Additionally, the project will cultivate a new generation of healthcare professionals equipped with practical skills in preventive medicine and health promotion, strengthening interprofessional teamwork and community outreach capacity.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Participants with hypertension, hyperglycemia, or hyperlipidemia who meet at least one of these criteria are eligible for enrollment.

Exclusion criteria

  • Age under 18 years
  • Patients diagnosed with neuromuscular disorders
  • Inability to perform cardiopulmonary exercise testing
  • Refusal to participate in the study

Treatment and study plan

Primary outcomes

  1. appendicular skeletal muscle mass index

    Time frame: From enrollment to the end of intervention at 12 months

    appendicular skeletal muscle mass (ASM) divided by height squared; low muscle mass is defined as ASMI < 7.0 kg/m² in men and < 5.7 kg/m² in women

  2. six minute walk test

    Time frame: From enrollment to the end of intervention at 12 months

    functional performance; higher scores mean a better outcome

Study contacts

Contact information is provided by the study sponsor or research team.

Ke-Yun Chao, PhD

CONTACT

[email protected]

+886-905-301-879

Sponsors and collaborators

Lead sponsor

Fu Jen Catholic University

Other

Registry information

Official study title

A Regional Integrated Care Innovation Program for Cardiometabolic Health, Pulmonary-Circulatory Disease Management, and Elderly Support

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
May 11, 2026
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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