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Completed

NCT Number: NCT04782726

Radiation Therapy Plan Quality Improvement Using Ideal Theoretical Isodose Distribution

The researchers hope that based on the study findings future patients may benefit from a more precise radiation treatment plan that can be developed more quickly and thus decrease the time from Computerized Tomography Simulation to start of treatment.

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Key information

Conditions

Head and Neck Neoplasms Neoplasms Neoplasms by Site

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mays Cancer Center

San Antonio, Texas, 78229, United States

About this study

As part of this study participants will receive the standard of care treatment for all head and neck cancer patients. The researchers plan to use a software program to see if it will assist in developing the best radiation treatment plan possible. The researchers will also measure the quality of each treatment plan so areas of improvement can be identified.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 18 years.
  • Ability to provide informed written consent in either English or Spanish.
  • Patient planned to undergo radiation therapy for Head and Neck Cancer.

Exclusion criteria

  • Current pregnancy, as this is a contraindication to receiving radiation therapy.
  • History of prior radiotherapy to the head and neck.
  • Any condition or history as evidenced by patient record and/or self-report that, in the opinion of the investigator, would interfere with adherence to daily radiation therapy.

Treatment and study plan

Software Solution for Radiation Therapy Treatment

Other

Software has been developed for individualized pre optimization evaluation of the patient anatomy and prescribed dose of radiation therapy.

Other names: Treatment planning

Radiation Therapy

Other

Standard of Care planning for Radiation therapy is used to treat the subjects for head and neck cancer

Other names: Radiation treatment

Primary outcomes

  1. Mean radiation dose to Organs at Risk (OAR)

    Time frame: Baseline to last treatment (up to 33 treatments or about 7 weeks)

    Measurement of radiation dose to organs at risk. The goal is to maintain the PTV (Planning Target Volume) coverage while minimizing the dose to organs at risk (OARs).

  2. Maximum radiation dose to Organs at Risk (OAR)

    Time frame: Baseline to last treatment (up to 33 treatments or about 7 weeks)

    Measurement of maximum radiation dose to organs at risk. The goal is to maintain the PTV (Planning Target Volume) coverage while minimizing the dose to organs at risk (OARs).

Secondary outcomes

  1. Time required to plan radiation therapy dose

    Time frame: CT Simulation to first treatment (about 1 week)

    The time required with and without individualized pre optimization information will be recorded and compared to determine efficiency.

Sponsors and collaborators

Lead sponsor

The University of Texas Health Science Center at San Antonio

Other

Registry information

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
Mar 4, 2021
Registry last updated
Jan 25, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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