London Health Sciences Centre
London, Ontario, N6A5A5, Canada
NCT Number: NCT03081663
This study is a randomized clinical trial comparing standard medial para-patellar total knee arthroplasty with a quadriceps sparing mid-vastus approach. Patients who are medically well and have a good support structure at home will be randomized to a standard or quadriceps sparing surgical approach stratified by type of analgesia (adductor canal block or local infiltration). We will compare patient satisfaction and costs from the perspective of the Ministry of Health, the institution, society and the patient.
Looking for future studies?
Notify Me18 year and older
All sexes
Interventional
Not applicable
London, Ontario, N6A5A5, Canada
Over the past 20 years the length of stay in hospital after total knee replacements has decreased from 9 days to 3 days in Canada and in just the last 10 years the mean length of stay has decreased by half from 6 to 3 days. In order to discharge patients quicker from hospital it's been theorized that less invasive techniques and better, longer lasting anaesthesia are required.
The less invasive quadriceps sparing mid-vastus approach for TKA has been compared to the standard medial para-patellar technique in many studies. Meta-analyses that have looked at studies comparing these approaches have shown some early advantages for quadriceps sparing early post-surgery, but no differences between groups later on and no difference in complications. Early advantages of the mid-vastus approach could potentially allow for earlier and safer discharge from hospital.
Adductor canal block (ACB) and local infiltration analgesia (LIA) form the mainstay of opioid sparing multimodal analgesia for TKA. The nerves of the adductor canal innervate the superficial and deep tissues of the anterior and medial aspects of the knee. ACB has been shown to provide equivalent analgesia while maintaining quadriceps power compared to femoral nerve block (FNB). LIA involves infiltrating the soft tissues of the posterior, lateral and medial aspects of the knee with local anesthetics, ketorolac and morphine. Due to their minimal impact on motor function, ACB and LIA are suitable for fast track TKA.
In combination, quadriceps sparing mid-vastus TKA with ACB may allow patients to be discharged from hospital quicker when compared with standard medial para-patellar TKA with LIA. With our study we aim to investigate whether a quadriceps sparing TKA can provide cost savings without changing complication rates when compared to the current standard of care.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Quadriceps-sparing mid-vastus approach for total knee arthroplasty
Other names: quads-sparing
Medial para-patellar approach for total knee arthroplasty
Other names: standard
Time frame: 1 year
ER visits, clinician visits, caregiver lost productivity, tests, etc.
Time frame: 1 year
Pain
Time frame: 1 year
Quality of Life
Time frame: 1 year
Functional Outcome
Time frame: 1 year
Functional Outcome
Time frame: 1 year
Quality of Life
Time frame: 1 year
Function
Time frame: 1 year
Falls, wound problems, pulmonary embolism, deep vein thrombosis, infection, etc.
Time frame: 6 weeks
Caregiver Confidence
Time frame: 6 weeks
Caregiver Strain
Time frame: 2 weeks
Patient satisfaction
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Other
Cost and Patient Satisfaction After Total Knee Arthroplasty: Standard Medial Para-patellar Versus Quadriceps Sparing Mid-vastus Surgical Approach
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04247802
Arthritis, Hip Arthroplasty
Banbury, Oxfordshire, United Kingdom
View Trial DetailsNCT04467970
Arthritis, Joint Diseases
Asyut, Egypt
View Trial DetailsNCT03276351
Arthritis, Joint Diseases
London, Ontario, Canada
View Trial DetailsNCT07212699
Alzheimer Disease, Arthritis
Munich, Bavaria, Germany
View Trial Details