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Completed

NCT Number: NCT04292782

Quadratus Lumborum Block for Pediatric Hip Surgery

Caudal blockade (CB) is one of the most frequently performed regional anaesthetic techniques in children. It's an efficient way to offer perioperative analgesia for painful sub-umbilical interventions but with high incidence of motor block and urinary retention. In one study, psoas compartment block was associated with less morphine comsumption and prolonged duration of analgesia compared to single-shot caudal Block in small children undergoing open hip reduction/osteotomies. Ultasound guided anterior Quadratus lumborum block (AQLB) provides unilateral analgesia to the nerves between the psoas muscle (PM) and the quadratus lumborum muscle (QLM). The first pediatric study evaluating Quadratus lumborum block is encouraging .

The first pediatric study evaluating Quadratus lumborum block is encouraging. To the best of the investigator's knowledge, there are no previously published data comparing the AQLB with other regional techniques in infants undergoing hip surgery.

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Key information

About this study

The aim of this prospective randomized study was to compare the analgesic effects between AQLB and CB in children undergoing unilateral open hip reduction/osteotomies for hip dislocation.

Patients were randomly assigned, into 1 of 2 groups, namely, group CB (n = 20) and group AQLB (n = 20).

Preoperatively all children were premedicated by using oral midazolam (0 .5mg/kg).

anesthesia was induced with 3 to 4% sevoflurane and 50% with 60% nitrous oxide in oxygen.Then fentanyl 3 μg/kg and Propofol 1 - 2mg/Kg were administered for anesthesia induction. Airway was secured with endotracheal tube placed in the mouth facilited by 0.15 mg/kg cistracurium. Anesthesia maintenance was performed with sevoflurane 2% in 50% nitrous oxide.

AQLB and CB were done with 1 ml/kg, 0.25% Ropivacaine (maximum dose limited to 20 ml)

Postoperative follow-up:

All patients received 15 mg/kg paracetamol before extubation. Tramadol 2 mg/kg intravenous was planned as rescue analgesia when CHEOPS score was more than 3. Supplemental IV tramado, 1 mg/kg could be added if necessary every 6 hours.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 2 to 7 years old
  • Weight ≤ 20 Kg
  • American Society of Anesthesiologists (ASA) physical status I or II
  • Planned to undergo unilateral open hip reduction/osteotomies

Exclusion criteria

  • Cerebral palsy with severe intellectual disability
  • Coagulation disorders
  • Local or general infection
  • Allergy to amide local anesthetics.
  • Progressive neurological disorders
  • Parenteral refusal
  • Spinal dysraphism
  • Cutaneous anomalies (angioma, hair truft, naevus or a dimple)near to the puncture

Treatment and study plan

Anterior quadratus lumborum block

Procedure

ultrasound anterior quadratum lumborum block with 1 ml/kg 0.2% ropivacaine

Caudal block

Procedure

ultrasound guided caudal block with 1 ml/kg 0.2% ropivacaine

Primary outcomes

  1. analgesics consumption

    Time frame: day one

    total tramadol consumption

Secondary outcomes

  1. postoperative pain score

    Time frame: day one

    Children's Hospital Eastern Ontario Pain Scale (CHEOPS) [4=no pain ; 13=worst pain]

  2. analgesic rescue

    Time frame: Day one

    time to first analgesic rescue

Sponsors and collaborators

Lead sponsor

University Tunis El Manar

Other

Collaborators

  • Institut Kassab d'Orthopédie

Registry information

Official study title

Caudal Epidural Block Compared to Anterior Quadratus Lumborum Block for Pediatric Hip Surgery

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Mar 3, 2020
Registry last updated
Feb 13, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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