QT-prolongation in Psychiatric Hospitals

Observational study in 6 psychiatric hospitals in Flanders. Patients are included when a QT-prolonging drug is added to a medication profile that already contains a potential QT-prolonging drug. An ECG is taken before the administration of the new drug and a week after starting the new drug to investigate the change in duration of the QTc-interval. Risk factors for developing QT-prolongation and blood concentrations of potassium and creatinine are documented.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

QT-prolongation Arrhythmias, Cardiac Cardiac Conduction System Disease Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Heart Defects, Congenital Heart Diseases Long QT Syndrome Pathologic Processes Pathological Conditions, Signs and Symptoms Tachycardia Tachycardia, Ventricular Torsades de Pointes

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Psychiatrisch Centrum Sint-Jan

Eeklo, Belgium

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

inpatient in one of the 6 participating psychiatric hospitals
QT-prolonging drug in the medication profile and the doctor prescribes another QT-prolonging drug

Exclusion criteria

age < 18 year

Treatment and study plan

drugs linked with QT-prolongation

Drug

all the drugs that are mentioned in the lists of QT-prolonging drugs of CredibleMeds (www.crediblemeds.org)

Primary outcomes

change in QTc-interval (corrected for heart rate)

Time frame: before and one week after the start of a QT-prolonging drug

Sponsors and collaborators

Lead sponsor

KU Leuven

Other

Collaborators

Agentschap voor Innovatie door Wetenschap en Technologie

Registry information

Important dates

Study start: 2010
Primary completion: 2015
Study completion: 2015
First posted: Jan 23, 2014
Registry last updated: Jul 28, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed