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OpenTrials
Completed

NCT Number: NCT01317511

Protein Supply in Elderly

Stimulating overnight muscle protein synthesis, might augment muscle hypertrophy, increase mitochondrial mass, and/or improve muscle tissue repair. The goal of this proposal will be to provide further insight into the responsiveness of the muscle protein synthetic machinery to food intake in relation to age.

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Key information

Conditions

Muscle Synthesis

Age range

65 year–80 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Maastricht University Medical Centre

Maastricht, Limburg, 6229ER, Netherlands

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Males
  • Age between 65 and 80 years
  • BMI < 30 kg/m2

Exclusion criteria

  • Type 2 diabetic patients
  • Use of medication
  • All co morbidities interacting with mobility and muscle metabolism of the lower limbs (e.g. artrosis, arthritis, spasticity/rigidity, all neurological disorders and paralysis).
  • Use of anticoagulants, blood diseases, allergy for lidocain.
  • Contra indications for the use of a nasogastric tube: high risk of aspiration, gastric stasis, gastro-oesophageal reflux, upper gastrointestinal stricture, nasal injuries and base of skull fractures.
  • Patients suffering from PKU (Phenylketonuria).

Treatment and study plan

Protein

Dietary Supplement

Protein drink

Other names: casein vs water

Primary outcomes

  1. Protein synthesis

    Time frame: overnight (12 h)

    Overnight protein synthesis

Sponsors and collaborators

Lead sponsor

Maastricht University Medical Center

Other

Registry information

Official study title

Overnight Protein Supply as a Dietary Strategy to Improve Muscle Mass in Elderly.

Important dates

Study start
2010
Primary completion
2010
Study completion
2011
First posted
Mar 17, 2011
Registry last updated
Mar 17, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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