The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Location status: Recruiting
Location contact
Paul Potnuru
CONTACT
Sudipta Sen, MD, FASA
CONTACT
NCT Number: NCT06654219
The purpose of this study is to determine if prolonged fasting from solids and transitioning to a CLD for 24 hours is protective to decrease RGC in patients on GLP-1 RAs presenting for upper endoscopy, to determine if prolonged fasting is associated with increased thirst, hunger and anxiety, To determine if signs and symptoms of nausea, vomiting, retching, abdominal bloating, and abdominal pain are present on the day of surgery, to see if there is any variability between preoperative gastric ultrasound assessment and volume of gastric contents visualized on upper endoscopy, to determine time of gastric emptying by serial Gastric ultrasonography (GUS) scans every 2 hours in subjects who presented with an initial at-risk scan, to determine the choice of anesthesia used based on preoperative GUS results, to determine if there were any adverse events recorded in this study group, to determine if duration of GLP-1 RA therapy has an association with residual gastric content (RGC). and to determine if dosing of GLP-1 RA has an association with RGC.
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Not applicable
Houston, Texas, 77030, United States
Location status: Recruiting
Paul Potnuru
CONTACT
Sudipta Sen, MD, FASA
CONTACT
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
NPO for solids: 24 hours prior to procedure, clear liquid diet (CLD) for 24 hours with last intake of clears no less than 2 hours prior to a procedure.GLP-1 RA will not be held prior to surgery and usual dosing schedule will be followed prior to procedure.
NPO after midnight prior to procedure; Minimum solid fasting duration of 8 hours for solids and 2 hours for liquids. Last dose of GLP-1 RA no less than 7 days prior to procedure.
Time frame: prior to procedure ( within 2 hours before procedure)
Participants with increased RGC will have solids, thick fluid, or clear fluids >1.5ml/kg in the gastric antrum in the right lateral decubitus position
Time frame: prior to procedure ( within 2 hours before procedure)
This is measured in a linear scale from 1-10, higher number showing worse outcome
Time frame: prior to procedure ( within 2 hours before procedure)
This is measured in a linear scale from 1-10, higher number showing worse outcome
Time frame: prior to procedure ( within 2 hours before procedure)
This is measured in a linear scale from 1-10, higher number showing worse outcome
Contact information is provided by the study sponsor or research team.
Paul Potnuru
CONTACT
Sudipta Sen, MD, FASA
CONTACT
The University of Texas Health Science Center, Houston
Other
Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor Agonist Prior to Anesthesia
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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