Skip to main content
OpenTrials
Completed

NCT Number: NCT05656690

Prospective Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults

Mobility loss in older people is caused by a variety of aging impairments in various body systems.The disability, which includes physical impairments and resulting activity limitations or participation restrictions, can arise acutely from a catastrophic illness or, more commonly, from subacute functional decline without a clear triggering event. Lower physical functioning was associated with higher healthcare utilization and expenditures, leading to a large burden on government-funded healthcare services. Early identification of mobility changes and intervening in them would likely be the most effective strategy to reduce the burden of disability in the population. Overall, there is a need to develop strategies to reduce disability among older adults in which kinetic and kinematic characteristics are used to predict disability status.

Accordingly, the purpose of this prospective cohort is to identify biomechanical parameters, from the gait, sit-to-stand, timed up and go, stair ascend and descend, and quiet standing functional tasks, as predictors of changes in health and disability status in older adults.

This research was funded by Fundação para a Ciência e Tecnologia (FCT), NORTE 2020, and European Social Fund of European Union, grant number 2020.05356.BD and through R&D Units funding (UIDB/05210/2020), Fundação para a Ciência e Tecnologia (FCT), Portugal and the European Union.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Disability

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Center for Rehabilitation Research, School of Health, Polytechnic of Porto, Portugal

Porto, 4200, Portugal

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • older adults, 60 years or over;
  • community-dwelling;
  • able to perform the tasks (gait, sit-to-stand, climb and descend stairs) independently;

Exclusion criteria

  • older adults who are institutionalized;
  • older adults who have established diagnosis of malignancy or terminal diseases with an anticipated survival of less than 1 year;
  • older adults who have stroke history, cerebral hemorrhage, head trauma, or Parkinson's disease;
  • older adults who have cognitive impairment, specifically Mini Mental StateExamination (Portuguese version) score of 22 for 0 to 2 years of literacy, 24 for 3 to6 years of literacy and 27 for more than 6 years of literacy (Morgado et al., 2009);
  • older adults who have rheumatic pathologies that interfere with the tasks performance;
  • older adults who have diabetic foot, lower limb fracture less than 6 weeks, or other related conditions;
  • older adults who have unstable cardiovascular disease, liver or renal function failure;
  • older adults who have a body mass index greater than or equal to 30 kg/m2;
  • older adults who vestibular and/or audition or vision impairments non corrected that influence the performance of tasks;
  • older adults who presence of symptoms at the time of evaluation that influences the participant performance of tasks.

Treatment and study plan

Exposure to disability

Other

Disability status assessed by functional measures

Primary outcomes

  1. Waveforms from full-body joint angles

    Time frame: Assessed once at study entry.

    Waveforms from full-body joint angles measured in degrees (°)

  2. Waveform from full-body angular joint velocities

    Time frame: Assessed once at study entry

    Waveform from angular joint velocities measured in degrees per second (°/s)

  3. Waveform from lower limb joint moments

    Time frame: Assessed once at study entry

    Waveform from lower limb joint moments measured in Newton-meter (kgm²/s²)

  4. Waveform from total body energy

    Time frame: Assessed once at study entry

    Waveform from total body energy measured in joules (J)

  5. Waveform from full-body separate segment energy

    Time frame: Assessed once at study entry

    Waveform from body segment energy un joules (J)

  6. Waveform from lower body joint forces

    Time frame: Assessed once at study entry

    Waveform from lower body joint forces measured in Newton (N)

  7. Waveform from lower body joint power

    Time frame: Assessed once at study entry

    Waveform from lower body joint power measured in Watts

  8. Waveform from centre of mass displacement

    Time frame: Assessed once at study entry

    Waveform from centre of mass displacement in m/s

  9. Waveform from centre of pressure displacement

    Time frame: Assessed once at study entry

    Waveform from centre of pressure displacement in m/s

  10. International Physical Activity Questionnaire

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    IPAQ is questionnaire to assess self-reported physical activity

  11. Mini-Mental State Examination (MMSE)

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    MMSE provides a brief screening test that quantitatively assesses the severity of cognitive impairment and documents cognitive changes occurring over time

  12. Barthel Index

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    The Barthel Index is an instrument that assesses the individual's level of independence for ten activities of daily living

  13. Lawton and Brody Instrumental Activities of Daily Living Scale

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    Lawton and Brody Instrumental Activities of Daily Living Scale assess the instrumental ADLs necessary for living in the community

  14. Number of health conditions

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    Total number and description of health conditions

  15. Number of falls

    Time frame: Assessed at study entry and evaluated every three months until the end of 1 year

    Total number and description of ocurrences of falls

Sponsors and collaborators

Lead sponsor

Polytechnic Institute of Porto

Other

Collaborators

  • Center for Rehabilitation Research - Polytechnic Institute of Porto (IPP)
  • School of Allied Health Sciences of Porto (ESTSP) - Polytechnic Institute of Porto (IPP)
  • Universidade do Porto

Registry information

Official study title

Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults Based on a Multifactorial Analysis: a Prospective Cohort Study

Acronym: MOBA-P

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Dec 19, 2022
Registry last updated
Nov 7, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.