Prospective Memory in Parkinson's Disease

The investigators tested whether prospective memory is impaired in individuals with Parkinson's Disease compared to controls using reliable and validated experimental measures. Also, the investigators assessed the impact of Parkinson's medication on prospective memory performance in PD to better estimate prospective memory function in PD patients' everyday (chronically treated) life.

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Key information

Conditions

Memory Basal Ganglia Diseases Brain Diseases Central Nervous System Diseases Movement Disorders Nervous System Diseases Neurodegenerative Diseases Parkinson Disease Parkinson's Disease Parkinsonian Disorders Prospective Memory Synucleinopathies

Age range

40 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Washington University School of Medicine

St Louis, Missouri, 63110, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

PD Group:

Clinically definite PD
40-70 years old
Hoehn and Yahr stage I,II,III
Currently treated with Levodopa/carbidopa
Control Group:

40-70 years old
Spouses of PD Group preferred

Exclusion criteria

PD Group and Control Group:

Significant neurological problems
Significant current psychiatric diagnoses
Mini Mental Status Exam score < 24 (MMSE)
Any significant abnormality on brain imaging
MPTP exposure
Control Participants met the same exclusion criteria described above as well as a biological family history of PD

Treatment and study plan

Primary outcomes

Virtual Week

Time frame: One session at baseline.

Prospective Memory Task; Score range is 0-100%, with higher scores being better performance.

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

National Institutes of Health (NIH)

Registry information

Acronym: ProMem

Important dates

Study start: 2009
Primary completion: 2010
Study completion: 2010
First posted: Jun 4, 2009
Registry last updated: May 6, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed