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Completed

NCT Number: NCT07564804

A Clinical Trial to Investigate the Efficacy of the Brain Blossom Supplement to Improve Cognitive Function and Memory

This study evaluates the efficacy of BioNatureHealth's Brain Blossom supplement in improving cognitive function and memory in adults aged 50-70 years. Participants will be randomized to receive either the test product or placebo over 8 weeks, with cognitive battery testing and questionnaires administered at multiple timepoints.

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Key information

Conditions

Cognitive Function Cognition Disorders Cognitive Decline Cognitive Dysfunction Memory Mental Disorders Neurocognitive Disorders

Age range

50 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Citruslabs

Las Vegas, Nevada, 89118, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or female
  • Aged 50-70 years
  • Seeking to support cognitive function and memory
  • Experiences at least three symptoms related to cognitive decline
  • Willing to avoid new cognitive-related medications/supplements
  • Generally healthy

Exclusion criteria

  • Medical conditions affecting cognition
  • Psychiatric or neurological disorders
  • Diabetes or heart conditions
  • Use of anticoagulants, benzodiazepines, or pain medications
  • Substance abuse or heavy alcohol use
  • Allergies to product ingredients
  • Inability to comply with protocol

Treatment and study plan

Dietary Supplement: Brain Blossom

Dietary Supplement

Six capsules taken once daily in the morning with water.

Placebo

Dietary Supplement

Rice flour capsules

Primary outcomes

  1. Change in Cognitive Battery Composite Score

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Cognitive function and memory will be assessed using a cognitive battery consisting of Polygons, Double Trouble, Feature Match, Paired Associates, Digit Span, and Spatial Planning tasks.

Secondary outcomes

  1. Change in Self-Reported Memory and Recall

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Assessed via study-specific questionnaires evaluating participants' perceived ability to retain and recall information.

  2. Change in Self-Reported Focus and Attentiveness

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Measured using questionnaire items assessing the ability to concentrate and maintain attention.

  3. Change in Self-Reported Comprehension

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Assessed via questionnaire responses evaluating participants' perceived ability to understand and process information.

  4. Change in Self-Reported Mental Clarity

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Measured through questionnaire items assessing clarity of thought and mental sharpness.

  5. Change in Self-Reported Learning Acuity

    Time frame: Baseline, Week 2, Week 4, Week 6, Week 8

    Assessed via questionnaire responses evaluating participants' perceived ability to learn and retain new information.

Sponsors and collaborators

Lead sponsor

Bio Nature Health

Industry

Collaborators

  • Citruslabs

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 4, 2026
Registry last updated
May 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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