Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients

Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular disease's population.

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Key information

Conditions

Home Mechanical Ventilation Nervous System Diseases Neuromuscular Disease Neuromuscular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hopital Raymond Poincare

Garches, 92380, France

About this study

Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficacy is mostly assessed by daytime blood gases and nocturnal oxymetry (SpO2). Transcutaneous CO2 measure (TcCO2) has shown higher sensitivity than SpO2 to detect hypoventilation in neuromuscular diseases (NMD) patients. No data exist on the prognostic value of these techniques to monitor mechanical ventilated NMD patients.

Basing on retrospective data review, investigators aimed to compare the prognostic value of the data obtained using different tools to assess residual hypoventilation in the cohort of ventilated NMD patients followed at our reference center.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

neuromuscular disease
age ≥18 years
mechanically ventilated
capno-oxymetry performed between 2009 and 2011

Exclusion criteria

Long-term oxygen therapy

Treatment and study plan

Capno-oxymetry monitoring

Device

Monitoring of home mechanical ventilation by capno-oximetry

Primary outcomes

Time to first ICU admission

Time frame: 6 years

Time to first ICU admission

Secondary outcomes

Mortality

Time frame: 6 years

Time to death

Sponsors and collaborators

Lead sponsor

Centre d'Investigation Clinique et Technologique 805

Other

Registry information

Acronym: TcCO2-VAD

Important dates

Study start: 2015
Primary completion: 2015
Study completion: 2015
First posted: Sep 16, 2015
Registry last updated: Feb 26, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed