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OpenTrials
Completed

NCT Number: NCT03113474

Profiling the Endocannabinoid Response to Hedonic Eating

Study into the endocannabinoid response to consuming a palatable versus a neutral food.

Completed

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Key information

Conditions

Obesity Behavior Body Weight Feeding Behavior Food Preferences Nutrition Disorders Nutritional and Metabolic Diseases Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy (self-report)
  • Dutch
  • Evaluating one of the used foods as palatable
  • Evaluating one of the used foods as neutral
  • Hb value between 8.1 and 11.0 mmol/L at screening

Exclusion criteria

  • restraint eating
  • lack of appetite
  • difficulties eating/swallowing
  • endocrine disorders
  • energy restricted diet two months prior to study
  • weight change > 5 kg in two months prior to study
  • stomach or bowel disease
  • taste or smell disorders (self-report)
  • not consuming foods used in the study
  • smoking > 1 cigarette per day
  • drinking > 21 units alcohol per week

Treatment and study plan

Food palatability

Other

Food palatability is modulated

Primary outcomes

  1. Endocannainoid levels

    Time frame: prior to, during and two hours after eating

    To assess changes in endocannabinoid plasma levels prior to, during and after eating a palatable versus a neutral food

Secondary outcomes

  1. Pancreatic polypeptide (pg/ml)

    Time frame: prior to, during and two hours after eating

    To assess changes in pancreatic polypeptide plasma levels prior to, during and after eating a palatable versus a neutral food

  2. Ghrelin (pg/ml)

    Time frame: prior to, during and two hours after eating

    To assess changes in ghrelin plasma levels prior to, during and after eating a palatable versus a neutral food

Sponsors and collaborators

Lead sponsor

Wageningen University

Other

Registry information

Acronym: Lekkere trek

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Apr 13, 2017
Registry last updated
May 24, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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